Dexmedetomidine and acute kidney injury following cardiac surgery in pediatric patients—An updated systematic review and meta-analysis

H Wang, C Zhang, Y Li, Y Jia, S Yuan… - Frontiers in …, 2022 - frontiersin.org
Background Acute kidney injury (AKI) is a common postoperative complication in pediatric
patients undergoing cardiac surgery and associated with poor outcomes. Dexmedetomidine …

Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury

JA Davidson, J Robison, L Khailova… - American Journal …, 2022 - journals.physiology.org
Acute kidney injury (AKI) is a common cause of morbidity after congenital heart disease
surgery. Progress on diagnosis and therapy remains limited, however, in part due to poor …

Pharmacological interventions for the prevention of acute kidney injury after pediatric cardiac surgery: a network meta-analysis

I Bellos, DC Iliopoulos, DN Perrea - Clinical and experimental nephrology, 2019 - Springer
Background Acute kidney injury constitutes a major complication of cardiac surgery in
pediatric patients. The present meta-analysis aims to accumulate current literature and …

Impact of different cardiopulmonary bypass strategies on renal injury after pediatric heart surgery

SD Tadphale, K Ramakrishnan, T Spentzas… - The Annals of Thoracic …, 2021 - Elsevier
Background The purpose of this study is to compare the incidence and severity of acute
kidney injury (AKI) after open heart surgery in neonates and infants for two different …

Effects of intraoperative dexmedetomidine on the incidence of acute kidney injury in pediatric cardiac surgery patients: a randomized controlled trial

EH Kim, JH Lee, HS Kim, YE Jang, SH Ji… - Pediatric …, 2020 - Wiley Online Library
Background Perioperative dexmedetomidine use has been reported to reduce the incidence
of postoperative acute kidney injury after adult cardiac surgery. However, large‐scale …

Alkaline phosphatase treatment of acute kidney injury in an infant piglet model of cardiopulmonary bypass with deep hypothermic circulatory arrest

JA Davidson, L Khailova, A Treece, J Robison… - Scientific reports, 2019 - nature.com
Acute kidney injury (AKI) is associated with prolonged hospitalization and mortality following
infant cardiac surgery, but therapeutic options are limited. Alkaline phosphatase (AP) …

Goal-directed perfusion to reduce acute kidney injury after paediatric cardiac surgery (GDP-AKIp): study protocol for a prospective randomised controlled trial

Y Zhang, X Zhou, B Wang, L Guo, R Zhou - BMJ open, 2020 - bmjopen.bmj.com
Introduction Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in up to 40%~
60% of paediatric patients and increases postoperative morbidity and mortality. A goal …

Protective effect of dexmedetomidine on kidney injury of parturients with preeclampsia undergoing cesarean section: a randomized controlled study

Q Zhang, L Wang, M Xu, T Wang - Bioscience Reports, 2019 - portlandpress.com
The present study aimed to elucidate the effects of dexmedetomidine on kidney injury of
parturients with preeclampsia (PE) undergoing cesarean section. Total 134 cesarean …

Effect of intraoperative theophylline use on acute kidney injury in paediatric cardiac surgery

Y Yavuz, FU Isildak - Cardiology in the Young, 2023 - cambridge.org
Background: This study aimed to examine the effects of theophylline use in preventing renal
dysfunction in patients undergoing CHD surgery. Methods: A total of 94 patients aged 1–60 …

[HTML][HTML] Molecular Basis of Kidney Injury and Repair: Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of …

JA Davidson, J Robison, L Khailova… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a common cause of morbidity after congenital heart disease
surgery. Progress on diagnosis and therapy remains limited, however, in part due to poor …