A guide to conquer the biological network era using graph theory

M Koutrouli, E Karatzas, D Paez-Espino… - … in bioengineering and …, 2020 - frontiersin.org
Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

Genomes OnLine Database (GOLD) v. 6: data updates and feature enhancements

S Mukherjee, D Stamatis, J Bertsch… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Genomes Online Database (GOLD)(https://gold. jgi. doe. gov) is a manually
curated data management system that catalogs sequencing projects with associated …

Biomolecule and bioentity interaction databases in systems biology: a comprehensive review

FA Baltoumas, S Zafeiropoulou, E Karatzas… - Biomolecules, 2021 - mdpi.com
Technological advances in high-throughput techniques have resulted in tremendous growth
of complex biological datasets providing evidence regarding various biomolecular …

FLAME: a web tool for functional and literature enrichment analysis of multiple gene lists

F Thanati, E Karatzas, FA Baltoumas, DJ Stravopodis… - Biology, 2021 - mdpi.com
Simple Summary Manipulation of multiple gene lists when going through a functional
enrichment analysis is often a hefty task. In this article, we present FLAME, a web application …

TeamTat: a collaborative text annotation tool

R Islamaj, D Kwon, S Kim, Z Lu - Nucleic acids research, 2020 - academic.oup.com
Manually annotated data is key to develo** text-mining and information-extraction
algorithms. However, human annotation requires considerable time, effort and expertise …

Darling: a web application for detecting disease-related biomedical entity associations with literature mining

E Karatzas, FA Baltoumas, I Kasionis, D Sanoudou… - Biomolecules, 2022 - mdpi.com
Finding, exploring and filtering frequent sentence-based associations between a disease
and a biomedical entity, co-mentioned in disease-related PubMed literature, is a challenge …

MER: a shell script and annotation server for minimal named entity recognition and linking

FM Couto, A Lamurias - Journal of cheminformatics, 2018 - Springer
Named-entity recognition aims at identifying the fragments of text that mention entities of
interest, that afterwards could be linked to a knowledge base where those entities are …

Flame (v2. 0): advanced integration and interpretation of functional enrichment results from multiple sources

E Karatzas, FA Baltoumas, E Aplakidou… - …, 2023 - academic.oup.com
Functional enrichment is the process of identifying implicated functional terms from a given
input list of genes or proteins. In this article, we present Flame (v2. 0), a web tool which offers …

PREGO: a literature and data-mining resource to associate microorganisms, biological processes, and environment types

H Zafeiropoulos, S Paragkamian, S Ninidakis… - Microorganisms, 2022 - mdpi.com
To elucidate ecosystem functioning, it is fundamental to recognize what processes occur in
which environments (where) and which microorganisms carry them out (who). Here, we …

OnTheFly2.0: a text-mining web application for automated biomedical entity recognition, document annotation, network and functional enrichment analysis

FA Baltoumas, S Zafeiropoulou… - NAR Genomics and …, 2021 - academic.oup.com
Extracting and processing information from documents is of great importance as lots of
experimental results and findings are stored in local files. Therefore, extracting and …