Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
K Achberger, C Probst, J Haderspeck, S Bolz, J Rogal… - elife, 2019 - elifesciences.org
The devastating effects and incurable nature of hereditary and sporadic retinal diseases
such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa …
such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa …
Animal models in eye research: focus on corneal pathologies
A Loiseau, G Raîche-Marcoux, C Maranda… - International Journal of …, 2023 - mdpi.com
The eye is a complex sensory organ that enables visual perception of the world. The
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …
Ocular toxicity of targeted therapies
DJ Renouf, JP Velazquez-Martin, R Simpson… - Journal of Clinical …, 2012 - ascopubs.org
Molecularly targeted agents are commonly used in oncology practice, and many new
targeted agents are currently being tested in clinical trials. Although these agents are …
targeted agents are currently being tested in clinical trials. Although these agents are …
Mechanistic study of silica nanoparticles on the size-dependent retinal toxicity in vitro and in vivo
Z Zhang, L Zhao, Y Ma, J Liu, Y Huang, X Fu… - Journal of …, 2022 - Springer
Abstract Background Silica nanoparticles (SiO2 NPs) are extensively applied in the
biomedical field. The increasing medical application of SiO2 NPs has raised concerns about …
biomedical field. The increasing medical application of SiO2 NPs has raised concerns about …
Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity
H Zou, JJ Koh, J Li, S Qiu, TT Aung, H Lin… - Journal of medicinal …, 2013 - ACS Publications
This work describes how to tune the amphiphilic conformation of α-mangostin, a natural
compound that contains a hydrophobic xanthone scaffold, to improve its antimicrobial …
compound that contains a hydrophobic xanthone scaffold, to improve its antimicrobial …
Breakdown of the blood-ocular barrier as a strategy for the systemic use of nanosystems
ML Occhiutto, FR Freitas, RC Maranhao, VP Costa - Pharmaceutics, 2012 - mdpi.com
Several drug delivery systems have been proposed to overcome physiological barriers,
improving ocular bioavailability. Systemic routes are seldom used due to the blood-ocular …
improving ocular bioavailability. Systemic routes are seldom used due to the blood-ocular …
Analytics, properties and applications of biologically active stilbene derivatives
M Kluska, J Jabłońska, W Prukała - Molecules, 2023 - mdpi.com
Stilbene and its derivatives belong to the group of biologically active compounds. Some
derivatives occur naturally in various plant species, while others are obtained by synthesis …
derivatives occur naturally in various plant species, while others are obtained by synthesis …
Microbiological isolates and antibiotic sensitivities in culture-proven endophthalmitis: a 15-year review
TP Moloney, J Park - British Journal of Ophthalmology, 2014 - bjo.bmj.com
Background To describe the microbiological spectrum and antibiotic sensitivities of
organisms causing culture-proven endophthalmitis in Queensland, Australia, and to …
organisms causing culture-proven endophthalmitis in Queensland, Australia, and to …
Microbiological isolates and antibiotic susceptibilities: a 10-year review of culture-proven endophthalmitis cases
C Liu, J Ji, S Li, Z Wang, L Tang, W Cao… - Current Eye …, 2017 - Taylor & Francis
Purpose: To review the microbiological spectrum and antibiotic sensitivities of the pathogens
that cause culture-proven endophthalmitis and to understand the status and trends of …
that cause culture-proven endophthalmitis and to understand the status and trends of …
Effects of cisplatin-5-fluorouracil combination therapy on oxidative stress, DNA damage, mitochondrial apoptosis, and death receptor signalling in retinal pigment …
H Güçlü, ZB Doganlar, VP Gürlü, A Özal… - Cutaneous and …, 2018 - Taylor & Francis
Aim: Combination therapies of cisplatin with 5-FU (PF) are an effective solution and have
been widely used for the treatment of various categories of cancer including anal …
been widely used for the treatment of various categories of cancer including anal …