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Multimorbidity and functional decline in community-dwelling adults: a systematic review
Background Multimorbidity affects up to one quarter of primary care populations. It is
associated with reduced quality of life, an increased risk of mental health difficulties and …
associated with reduced quality of life, an increased risk of mental health difficulties and …
Malnutrition in older adults: screening and determinants
Older adults are at risk of protein-energy malnutrition (PEM). PEM detrimentally impacts on
health, cognitive and physical functioning and quality of life. Given these negative health …
health, cognitive and physical functioning and quality of life. Given these negative health …
GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality
The aging process is characterized by the presence of high interindividual variation between
individuals of the same chronical age prompting a search for biomarkers that capture this …
individuals of the same chronical age prompting a search for biomarkers that capture this …
Anxiety, depression, loneliness and social network in the elderly: Longitudinal associations from The Irish Longitudinal Study on Ageing (TILDA)
Background Social network, loneliness, generalized anxiety disorder (GAD) and major
depression disorder (MDD) are interrelated. However, as the directions of these …
depression disorder (MDD) are interrelated. However, as the directions of these …
Social relationships, loneliness, and mental health among older men and women in Ireland: A prospective community-based study
Background Data is lacking on the association of interpersonal stressors and social isolation
with mental disorders and the mediating role of loneliness. Thus, we examined this …
with mental disorders and the mediating role of loneliness. Thus, we examined this …
Cohort profile update: the Irish longitudinal study on ageing (TILDA)
OA Donoghue, CA McGarrigle, M Foley… - International journal …, 2018 - academic.oup.com
As outlined in the original cohort profile, 1 The Irish Longitudinal Study on Ageing (TILDA) is
a prospective cohort study designed to provide an evidence base for addressing the …
a prospective cohort study designed to provide an evidence base for addressing the …
Loneliness, social networks, and health: a cross-sectional study in three countries
Objective It is widely recognized that social networks and loneliness have effects on health.
The present study assesses the differential association that the components of the social …
The present study assesses the differential association that the components of the social …
Polypharmacy including falls risk-increasing medications and subsequent falls in community-dwelling middle-aged and older adults
Background: polypharmacy is an important risk factor for falls, but recent studies suggest
only when including medications associated with increasing the risk of falls. Design: a …
only when including medications associated with increasing the risk of falls. Design: a …
Validation of the 8-item Centre for Epidemiological Studies Depression Scale in a cohort of community-dwelling older people: data from The Irish Longitudinal Study …
Background The aim of this study was to validate the 8-item Centre for Epidemiological
Studies Depression Scale (CES-D-8) against the 20-item version (CES-D-20) in a large …
Studies Depression Scale (CES-D-8) against the 20-item version (CES-D-20) in a large …
Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks
Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …
experience of childhood adversity was associated with epigenetic age acceleration in mid …