Single-molecule localization microscopy
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
Disruptive technologies as a solution for disaster risk management: A review
Integrating disruptive technologies within smart cities improves the infrastructure needed to
potentially deal with disasters. This paper provides a perspective review of disruptive …
potentially deal with disasters. This paper provides a perspective review of disruptive …
Structural basis of NINJ1-mediated plasma membrane rupture in cell death
M Degen, JC Santos, K Pluhackova, G Cebrero… - Nature, 2023 - nature.com
Eukaryotic cells can undergo different forms of programmed cell death, many of which
culminate in plasma membrane rupture as the defining terminal event,,,,,–. Plasma …
culminate in plasma membrane rupture as the defining terminal event,,,,,–. Plasma …
Conservation and divergence of cortical cell organization in human and mouse revealed by MERFISH
The human cerebral cortex has tremendous cellular diversity. How different cell types are
organized in the human cortex and how cellular organization varies across species remain …
organized in the human cortex and how cellular organization varies across species remain …
Democratising deep learning for microscopy with ZeroCostDL4Mic
Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …
outperform conventional image processing pipelines. Despite the enthusiasm and …
Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease
Soluble α-synuclein aggregates varying in size, structure, and morphology have been
closely linked to neuronal death in Parkinson's disease. However, the heterogeneity of …
closely linked to neuronal death in Parkinson's disease. However, the heterogeneity of …
[HTML][HTML] The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
K Cosentino, V Hertlein, A Jenner, T Dellmann… - Molecular cell, 2022 - cell.com
BAX and BAK are key apoptosis regulators that mediate the decisive step of mitochondrial
outer membrane permeabilization. However, the mechanism by which they assemble the …
outer membrane permeabilization. However, the mechanism by which they assemble the …
Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1
It remains unclear why acute depletion of CTCF (CCCTC-binding factor) and cohesin only
marginally affects expression of most genes despite substantially perturbing three …
marginally affects expression of most genes despite substantially perturbing three …
The cellular response to extracellular vesicles is dependent on their cell source and dose
Extracellular vesicles (EVs) have been established to play important roles in cell-cell
communication and shown promise as therapeutic agents. However, we still lack a basic …
communication and shown promise as therapeutic agents. However, we still lack a basic …
Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling
SE Anton, C Kayser, I Maiellaro, K Nemec, J Möller… - Cell, 2022 - cell.com
G protein-coupled receptors (GPCRs) relay extracellular stimuli into specific cellular
functions. Cells express many different GPCRs, but all these GPCRs signal to only a few …
functions. Cells express many different GPCRs, but all these GPCRs signal to only a few …