Simple Summary Microsatellite instability (MSI) is a hallmark of Lynch syndrome (LS)-related
tumors but is not specific, as most of MSI/mismatch repair-deficient (dMMR) tumors are …

Muir-Torre syndrome (MTS) is a rare genetic condition that predisposes individuals to skin
tumors and visceral malignancies. Because of the potentially aggressive nature of internal …

Muir-Torre syndrome is an autosomal-dominant skin condition of genetic origin,
characterised by tumours of the sebaceous gland or keratoacanthoma that are associated …

Lynch syndrome is the predisposition to visceral malignancies that are associated with
deleterious germline mutations in DNA mismatch repair genes, including MLH1, MSH2 …

Sebaceous neoplasms have long been a source of confusion to dermatologists and
pathologists alike. Disagreements regarding nomenclature, classification, and management …

BACKGROUND. Sebaceous tumors of the skin occurring in association with an internal
malignancy characterize Muir‐Torre syndrome (MTS), a variant of hereditary nonpolyposis …

Although the majority of gastric carcinomas are sporadic, approximately 10% show familial
aggregation, and a hereditary cause is determined in 1%–3% cases. Of these, hereditary …

Hereditary Nonpolyposis Colorectal Cancer (HNPCC), also known as Lynch Syndrome, is
an autosomal dominant, tumor predisposing disorder usuallycaused by germline mutations …

Muir-Torre syndrome (MTS) is a rare autosomal-dominant genodermatosis characterized by
sebaceous neoplasms and one or more visceral malignancies. Sebaceous tumors include …

A subset of patients with Lynch Syndrome demonstrates cutaneous manifestations of the
disorder. Characterization of these Lynch-related skin lesions could help in early recognition …