Circular RNA in cancer
Over the past decade, circular RNA (circRNA) research has evolved into a bona fide
research field shedding light on the functional consequence of this unique family of RNA …
research field shedding light on the functional consequence of this unique family of RNA …
Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression
C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …
CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer
T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular Cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …
Circular RNAs: characteristics, biogenesis, mechanisms and functions in liver cancer
H Shen, B Liu, J Xu, B Zhang, Y Wang, L Shi… - Journal of Hematology & …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies
globally. Despite aggressive and multimodal treatment regimens, the overall survival of HCC …
globally. Despite aggressive and multimodal treatment regimens, the overall survival of HCC …
RNA-based diagnostic markers discovery and therapeutic targets development in cancer
H Wang, Q Meng, J Qian, M Li, C Gu, Y Yang - Pharmacology & …, 2022 - Elsevier
The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …
treatment, and to provide novel insights into their clinical applications. RNAs, including …
Engineered extracellular vesicles for bone therapy
Extracellular vesicles, which are secreted by living cells and play a critical role in cellular
communication, have emerged as a promising cell-free strategy in the treatment of many …
communication, have emerged as a promising cell-free strategy in the treatment of many …
CircRNAs and their regulatory roles in cancers
M Tao, M Zheng, Y Xu, S Ma, W Zhang, S Ju - Molecular Medicine, 2021 - Springer
Circular RNAs (circRNAs), a novel type of non-coding RNAs (ncRNAs), have a covalently
closed circular structure resulting from pre-mRNA back splicing via spliceosome and …
closed circular structure resulting from pre-mRNA back splicing via spliceosome and …
CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis
Abstract Background Circular RNAs (circRNAs), a class of noncoding RNAs (ncRNAs), may
modulate gene expression by binding to miRNAs. Additionally, recent studies show that …
modulate gene expression by binding to miRNAs. Additionally, recent studies show that …
Circular RNAs' cap-independent translation protein and its roles in carcinomas
L He, C Man, S **ang, L Yao, X Wang, Y Fan - Molecular cancer, 2021 - Springer
Circular RNAs a kind of covalently closed RNA and widely expressed in eukaryotes.
CircRNAs are involved in a variety of physiological and pathological processes, but their …
CircRNAs are involved in a variety of physiological and pathological processes, but their …