Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …
infected and nearly six million dead worldwide, making it the most significant pandemic …
[HTML][HTML] Cytokine Storm in COVID-19: Exploring IL-6 Signaling and Cytokine-Microbiome Interactions as Emerging Therapeutic Approaches
IL-6 remains a key molecule of the cytokine storms characterizing COVID-19, exerting both
proinflammatory and anti-inflammatory effects. Emerging research underscores the …
proinflammatory and anti-inflammatory effects. Emerging research underscores the …
Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response
A Santa Cruz, A Mendes-Frias… - Nature …, 2023 - nature.com
Several millions of individuals are estimated to develop post-acute sequelae SARS-CoV-2
condition (PASC) that persists for months after infection. Here we evaluate the immune …
condition (PASC) that persists for months after infection. Here we evaluate the immune …
Respiratory distress in SARS-CoV-2 exposed uninfected neonates followed in the COVID Outcomes in Mother-Infant Pairs (COMP) Study
Respiratory distress (RD) has been reported in SARS-CoV-2 exposed uninfected (SEU)
term neonates. Prior studies suggest that prenatal exposure to Coronavirus Disease 19 …
term neonates. Prior studies suggest that prenatal exposure to Coronavirus Disease 19 …
Metagenomic assessment of gut microbial communities and risk of severe COVID-19
Background The gut microbiome is a critical modulator of host immunity and is linked to the
immune response to respiratory viral infections. However, few studies have gone beyond …
immune response to respiratory viral infections. However, few studies have gone beyond …
Explanatory predictive model for COVID-19 severity risk employing machine learning, shapley addition, and LIME
The rapid spread of SARS-CoV-2 threatens global public health and impedes the operation
of healthcare systems. Several studies have been conducted to confirm SARS-CoV-2 …
of healthcare systems. Several studies have been conducted to confirm SARS-CoV-2 …
Prognostic markers in hospitalized COVID‐19 patients: the role of IP‐10 and C‐reactive protein
M Rizzi, M Costanzo, S Tonello, E Matino… - Disease …, 2022 - Wiley Online Library
Background. SARS‐CoV‐2 is responsible for COVID‐19, a clinically heterogeneous
disease, ranging from being completely asymptomatic to life‐threating manifestations. An …
disease, ranging from being completely asymptomatic to life‐threating manifestations. An …
Role of innate and adaptive cytokines in the survival of COVID-19 patients
J Monserrat, A Gómez-Lahoz, MA Ortega… - International journal of …, 2022 - mdpi.com
SARS-CoV-2 is a new coronavirus characterized by a high infection and transmission
capacity. A significant number of patients develop inadequate immune responses that …
capacity. A significant number of patients develop inadequate immune responses that …
Effect of lactoferrin on clinical outcomes of hospitalized patients with COVID-19: the LAC randomized clinical trial
As lactoferrin is a nutritional supplement with proven antiviral and immunomodulatory
abilities, it may be used to improve the clinical course of COVID-19. The clinical efficacy and …
abilities, it may be used to improve the clinical course of COVID-19. The clinical efficacy and …
Comparing machine learning screening approaches using clinical data and cytokine profiles for COVID-19 in resource-limited and resource-abundant settings
HH Rashidi, A Ikram, LT Dang, A Bashir, T Zohra… - Scientific Reports, 2024 - nature.com
Accurate screening of COVID-19 infection status for symptomatic patients is a critical public
health task. Although molecular and antigen tests now exist for COVID-19, in resource …
health task. Although molecular and antigen tests now exist for COVID-19, in resource …