Supercritical carbon dioxide (SC‐CO2) is CO2 that is stored beyond its critical point of 7.4
MPa and 31.1° C. Given the request for consumption of a green solvent for the environment …

Poor water solubility and poor bioavailability are problems with many pharmaceuticals.
Increasing surface area by micronization is an effective strategy to overcome these …

Supercritical fluid (SCF) processes have attracted great attention for fabricating micro and
nanoparticles in the pharmaceutical applications. Herein we utilized, for the first time, Gas …

Supercritical processes are utilized in pharmaceutical, chemical, agricultural and food
industries. To design the micro or nanoparticles formation processes via a supercritical fluid …

A reduction in particle size improves the solubility and bioavailability of pharmaceuticals.
The traditional methods utilized in this regard are associated with problems so the use of …

Many new chemical entities (NCEs) have been discovered with the development of the
pharmaceutical industry. However, the main disadvantage of these drugs is their low …

Reducing the size of pharmaceutical particles is an approved way to enhance solubility and
bioavailability of a drug, leading to a decrease in the drug dose and its side effects. In this …

Phthalocyanine green nano pigment was prepared using supercritical gas antisolvent (GAS)
process based on the SC-CO 2 method. Thermodynamic models were developed to study …

Glibenclamide is an antidiabetic drug that also acts as an anti-inflammatory factor and
reduces oxidative stress, medullary edema, and heart attack. Glibenclamide has high …

A novel anti-clogging strategy by combining ultrasound and segmented flow was proposed
and successfully applied to continuous crystallization process. The individual anti-clogging …