Biomaterials with suitable surface modification strategies are contributing significantly to the
rapid development of the field of bone tissue engineering. Despite these encouraging …

Biomedical implants have been widely used in various orthopedic treatments, including total
hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern …

Osseointegration is a sophisticated bone and implant healing process comprising of initial
hematoma formation, immediate osteoimmunomodulation, angiogenesis, and osteogenesis …

The immune microenvironment induced by biomaterials played vital roles in bone
regeneration. Hydroxyapatite (HA) and its ion-substituted derivates represent a large class …

Osseointegration of implants is a complex physiological process that requires temporal and
spatial regulation of immune responses, angiogenesis, and osteogenesis. To achieve …

Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Physical cues like morphology, light, electric signal, mechanic signal, magnetic signal, and
heat can be used as alternative regulators for expensive but short‐acting growth factors in …

Manipulations of morphological properties of nanobiomaterials have been demonstrated to
modulate the outcome of osteoimmunomodulation and eventually osteogenesis through …

Titanium and its alloys are dominant material for orthopedic/dental implants due to their
stable chemical properties and good biocompatibility. However, aseptic loosening and peri …

Metallic biomaterials are widely used in implants to strengthen, repair, or replace damaged
bone tissue, and their material characteristics have direct influences on short-and long-term …