Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
[HTML][HTML] Microfluidics-derived microcarrier systems for oral delivery
Oral delivery is with high patient compliance but low bioavailability and controllability. The
emerging microfluidics-derived microcarriers have sprung up to relieve the hurdles. Herein …
emerging microfluidics-derived microcarriers have sprung up to relieve the hurdles. Herein …
Synthesis and characterization of a novel, pH-responsive sustained release nanocarrier using polyethylene glycol, graphene oxide, and natural silk fibroin protein by …
PA Jeshvaghani, M Pourmadadi, F Yazdian… - International Journal of …, 2023 - Elsevier
In this study, for the first time, by employing a simple and efficient double nano-emulsification
method and using sweet almond oil as the organic phase, polyethylene glycol …
method and using sweet almond oil as the organic phase, polyethylene glycol …
[HTML][HTML] Zweifach–Fung Microfluidic Device for Efficient Microparticle Separation: Cost-Effective Fabrication Using CO2 Laser-Ablated PMMA
Microfluidic separators play a pivotal role in the biomedical and chemical industries by
enabling precise fluid manipulations. Traditional fabrication of these devices typically …
enabling precise fluid manipulations. Traditional fabrication of these devices typically …
A novel fluorinated polyethyleneimine with microRNA-942-5p-sponges polyplex gene delivery system for non-small-cell lung cancer therapy
Y **, W Yu, W Zhang, C Wang, Y Liu, WE Yuan… - Journal of Colloid and …, 2023 - Elsevier
Gene delivery for non-small-cell lung cancer treatment has been a challenge due to low
nucleic acid binding ability, cell-wall barrier, and high cytotoxicity. Cationic polymers, such …
nucleic acid binding ability, cell-wall barrier, and high cytotoxicity. Cationic polymers, such …
Delivery and assessment of a CRISPR/nCas9-based genome editing system on in vitro models of mucopolysaccharidoses IVA assisted by magnetite-based …
Abstract Mucopolysaccharidosis IV A (MPS IVA) is a lysosomal disorder caused by
mutations in the GALNS gene. Consequently, the glycosaminoglycans (GAGs) keratan …
mutations in the GALNS gene. Consequently, the glycosaminoglycans (GAGs) keratan …
Microfluidic synthesis of lipid-based nanoparticles for drug delivery: recent advances and opportunities
Microfluidic technologies are revolutionizing the synthesis of nanoscale lipid particles and
enabling new opportunities for the production of lipid-based nanomedicines. By harnessing …
enabling new opportunities for the production of lipid-based nanomedicines. By harnessing …
[HTML][HTML] Enhancing magnetic micro-and nanoparticle separation with a cost-effective microfluidic device fabricated by laser ablation of PMMA
Superparamagnetic iron oxide micro-and nanoparticles have significant applications in
biomedical and chemical engineering. This study presents the development and evaluation …
biomedical and chemical engineering. This study presents the development and evaluation …
Nanotechnology-enabled gene delivery for cancer and other genetic diseases
T Jiang, KM Gonzalez, LE Cordova… - Expert opinion on drug …, 2023 - Taylor & Francis
Introduction Despite gene therapy is ideal for genetic abnormality-related diseases, the easy
degradation, poor targeting, and inefficiency in entering targeted cells are plaguing the …
degradation, poor targeting, and inefficiency in entering targeted cells are plaguing the …
Enhanced Delivery and Potency of Chemotherapeutics in Melanoma Treatment via Magnetite Nanobioconjugates
Melanoma, known for its aggressive metastatic potential, poses significant treatment
challenges. Despite the potent antiproliferative effects of anticancer drugs, systemic toxicity …
challenges. Despite the potent antiproliferative effects of anticancer drugs, systemic toxicity …