Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

The mutual interplay of gut microbiota, diet and human disease

P Illiano, R Brambilla, C Parolini - The FEBS journal, 2020 - Wiley Online Library
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

Small intestine microbiota regulate host digestive and absorptive adaptive responses to dietary lipids

K Martinez-Guryn, N Hubert, K Frazier, S Urlass… - Cell host & …, 2018 - cell.com
The gut microbiota play important roles in lipid metabolism and absorption. However, the
contribution of the small bowel microbiota of mammals to these diet-microbe interactions …

Proteobacteria: microbial signature of dysbiosis in gut microbiota

NR Shin, TW Whon, JW Bae - Trends in biotechnology, 2015 - cell.com
Recent advances in sequencing techniques, applied to the study of microbial communities,
have provided compelling evidence that the mammalian intestinal tract harbors a complex …

Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment

MA Malla, A Dubey, A Kumar, S Yadav… - Frontiers in …, 2019 - frontiersin.org
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …

Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis

M Pammi, J Cope, PI Tarr, BB Warner, AL Morrow… - Microbiome, 2017 - Springer
Background Necrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants, and
microbial dysbiosis has been implicated in its pathogenesis. Studies evaluating the …

The composition of the gut microbiota throughout life, with an emphasis on early life

JM Rodríguez, K Murphy, C Stanton… - Microbial ecology in …, 2015 - Taylor & Francis
The intestinal microbiota has become a relevant aspect of human health. Microbial
colonization runs in parallel with immune system maturation and plays a role in intestinal …

Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease

MR Minter, C Zhang, V Leone, DL Ringus, X Zhang… - Scientific reports, 2016 - nature.com
Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features
of Alzheimer's disease (AD). In addition to astrocyte and microglial reactivity, emerging …

Clinical implications of preterm infant gut microbiome development

DB Healy, CA Ryan, RP Ross, C Stanton… - Nature …, 2022 - nature.com
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

[HTML][HTML] Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism

V Leone, SM Gibbons, K Martinez, AL Hutchison… - Cell host & …, 2015 - cell.com
Circadian clocks and metabolism are inextricably intertwined, where central and hepatic
circadian clocks coordinate metabolic events in response to light-dark and sleep-wake …