SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines

R Sartorius, M Trovato, R Manco, L D'Apice… - npj Vaccines, 2021 - nature.com
Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-
recognition receptors. They function as sensors of invading pathogens through recognition …

Fast-track development of vaccines for SARS-CoV-2: the shots that saved the world

VP Chavda, Q Yao, LK Vora, V Apostolopoulos… - Frontiers in …, 2022 - frontiersin.org
In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …

Toll-like receptors as a therapeutic target in the era of immunotherapies

M Farooq, M Batool, MS Kim, S Choi - Frontiers in Cell and …, 2021 - frontiersin.org
Toll-like receptors (TLRs) are the pattern recognition receptors, which are activated by
foreign and host molecules in order to initiate the immune response. They play a crucial role …

COVID-19 and vaccination: myths vs science

VP Chavda, Y Chen, J Dave, ZS Chen… - Expert Review of …, 2022 - Taylor & Francis
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …

A review of human coronaviruses' receptors: the host-cell targets for the crown bearing viruses

A Nassar, IM Ibrahim, FG Amin, M Magdy, AM Elgharib… - Molecules, 2021 - mdpi.com
A novel human coronavirus prompted considerable worry at the end of the year 2019. Now,
it represents a significant global health and economic burden. The newly emerged …

Current understanding of multisystem inflammatory syndrome (MIS-C) following COVID-19 and its distinction from Kawasaki disease

H Bukulmez - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review In this article, I have reviewed current reports that explore
differences and similarities between multisystem inflammatory syndrome in children (MIS-C) …

Inflammatory mediators of platelet activation: focus on atherosclerosis and COVID-19

P Theofilis, M Sagris, AS Antonopoulos… - International Journal of …, 2021 - mdpi.com
Background: Atherosclerotic cardiovascular diseases are characterized by a dysregulated
inflammatory and thrombotic state, leading to devastating complications with increased …

Plasmacytoid dendritic cells depletion and elevation of IFN-γ dependent chemokines CXCL9 and CXCL10 in children with multisystem inflammatory syndrome

F Caldarale, M Giacomelli, E Garrafa… - Frontiers in …, 2021 - frontiersin.org
Background SARS-CoV-2 occurs in the majority of children as COVID-19, without symptoms
or with a paucisymptomatic respiratory syndrome, but a small proportion of children develop …