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Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …
therapeutics as they improve the pharmacokinetic profile and distribution of …
Incorporating selenium into heterocycles and natural products─ from chemical properties to pharmacological activities
W Hou, H Xu - Journal of Medicinal Chemistry, 2022 - ACS Publications
Selenium (Se)-containing compounds have emerged as potential therapeutic agents for the
treatment of a range of diseases. Through tremendous effort, considerable knowledge has …
treatment of a range of diseases. Through tremendous effort, considerable knowledge has …
Zinc, magnesium, selenium and depression: a review of the evidence, potential mechanisms and implications
Micronutrient deficiency and depression are major global health problems. Here, we first
review recent empirical evidence of the association between several micronutrients—zinc …
review recent empirical evidence of the association between several micronutrients—zinc …
The role of selenium in arsenic and cadmium toxicity: an updated review of scientific literature
I Zwolak - Biological trace element research, 2020 - Springer
Abstract Arsenic (As) and cadmium (Cd) are elements arousing major public health
concerns associated with environmental pollution, high toxicity potential, and carcinogenic …
concerns associated with environmental pollution, high toxicity potential, and carcinogenic …
Selenium: environmental significance, pollution, and biological treatment technologies
10Selenium is an essential trace element needed for all living organisms. Despite its
essentiality, selenium is a potential toxic element to natural ecosystems due to its …
essentiality, selenium is a potential toxic element to natural ecosystems due to its …
Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease
The biological activity of selenium is dependent upon its speciation. We aim to integrate
selenium speciation and metabolism into a discussion of the mechanisms by which …
selenium speciation and metabolism into a discussion of the mechanisms by which …
[HTML][HTML] Selenium compounds as novel potential anticancer agents
D Radomska, R Czarnomysy, D Radomski… - International journal of …, 2021 - mdpi.com
The high number of new cancer incidences and the associated mortality continue to be
alarming, leading to the search for new therapies that would be more effective and less …
alarming, leading to the search for new therapies that would be more effective and less …
Selenium as an emerging versatile player in heterocycles and natural products modification
W Hou, H Dong, X Zhang, Y Wang, L Su, H Xu - Drug Discovery Today, 2022 - Elsevier
The diverse pharmacological activities of organoselenium compounds are closely correlated
to their ability to scavenge and induce reactive oxygen species (ROS), their intrinsic …
to their ability to scavenge and induce reactive oxygen species (ROS), their intrinsic …
Synthesis and in Silico Investigation of Organoselenium-Clubbed Schiff Bases as Potential Mpro Inhibitors for the SARS-CoV-2 Replication
Simple Summary The coronavirus was declared a worldwide pandemic for the first time in
December 2019. Although vaccination reduces the risk of severe illness and death, no …
December 2019. Although vaccination reduces the risk of severe illness and death, no …