The hunger strikes back: an epigenetic memory for autophagy
Historical and demographical human cohorts of populations exposed to famine, as well as
animal studies, revealed that exposure to food deprivation is associated to lasting health …
animal studies, revealed that exposure to food deprivation is associated to lasting health …
[HTML][HTML] Dysregulation of different modes of programmed cell death by epigenetic modifications and their role in cancer
R Damiescu, T Efferth, M Dawood - Cancer Letters, 2024 - Elsevier
Modifications of epigenetic factors affect our lives and can give important information
regarding one's state of health. In cancer, epigenetic modifications play a crucial role, as …
regarding one's state of health. In cancer, epigenetic modifications play a crucial role, as …
Integrated miRNA and mRNA omics reveal neferine induced autophagy-dependent ferroptosis in human endometrial cancer in vivo and in vitro
The most frequent type of gynecological cancer, endometrial cancer, seriously jeopardizes
the health of women. Lotus seed embryos contain large amounts of the compound neferine …
the health of women. Lotus seed embryos contain large amounts of the compound neferine …
Aspirin exposure coupled with hypoxia interferes energy metabolism, antioxidant and autophagic processes and causes liver injury in estuarine goby Mugilogobius …
Y Wang, Y Zhao, W Gong, Y Hou, J Ren, C Duan… - Journal of Hazardous …, 2024 - Elsevier
Toxicity assessments of pollutants often overlook the impact of environmental factors like
hypoxia, which can alter chemical toxicity with unexpected consequences. In this study …
hypoxia, which can alter chemical toxicity with unexpected consequences. In this study …
Targeting TRIP13 for overcoming anticancer drug resistance
L Zhao, S Ye, S **g, YJ Gao, T He - Oncology Reports, 2023 - spandidos-publications.com
Cancer is one of the greatest dangers to human wellbeing and survival. A key barrier to
effective cancer therapy is development of resistance to anti-cancer medications. In cancer …
effective cancer therapy is development of resistance to anti-cancer medications. In cancer …
Effects of Bryophyllum pinnatum on Dysfunctional Autophagy in Rats Lungs Exposed to Zinc Oxide Nanoparticles
Lung inflammation as a result of exposure to toxicants is a major pathological problem.
Autophagy (AP) is a process of cell self-digestion and can be disrupted by environmental …
Autophagy (AP) is a process of cell self-digestion and can be disrupted by environmental …
Targeting autophagy drug discovery: Targets, indications and development trends
M Jiang, W Wu, Z **ong, X Yu, Z Ye, Z Wu - European Journal of Medicinal …, 2024 - Elsevier
Autophagy plays a vital role in sustaining cellular homeostasis and its alterations have been
implicated in the etiology of many diseases. Drugs development targeting autophagy began …
implicated in the etiology of many diseases. Drugs development targeting autophagy began …
[HTML][HTML] The Antitumor Potential of Sicilian Grape Pomace Extract: A Balance between ROS-Mediated Autophagy and Apoptosis
F Affranchi, D Di Liberto, M Lauricella, A D'Anneo… - Biomolecules, 2024 - mdpi.com
From the perspective of circular economy, it is extremely useful to recycle waste products for
human health applications. Among the health-beneficial properties of bioactive phyto …
human health applications. Among the health-beneficial properties of bioactive phyto …
The assessment of anti-melanoma potential of tigecycline—cellular and molecular studies of cell proliferation, apoptosis and autophagy on amelanotic and melanotic …
J Rok, J Kowalska, Z Rzepka, D Stencel, A Skorek… - Cells, 2023 - mdpi.com
High mortality, aggressiveness, and the relatively low effectiveness of therapy make
melanoma the most dangerous of skin cancers. Previously published studies presented the …
melanoma the most dangerous of skin cancers. Previously published studies presented the …
[HTML][HTML] The Interplay between Autophagy and Mitochondria in Cancer
A Zdanowicz, E Grosicka-Maciąg - International Journal of Molecular …, 2024 - mdpi.com
Besides producing cellular energy, mitochondria are crucial in controlling oxidative stress
and modulating cellular metabolism, particularly under stressful conditions. A key aspect of …
and modulating cellular metabolism, particularly under stressful conditions. A key aspect of …