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Gut-derived low-grade endotoxaemia, atherothrombosis and cardiovascular disease
Systemic inflammation has been suggested to have a pivotal role in atherothrombosis, but
the factors that trigger systemic inflammation have not been fully elucidated …
the factors that trigger systemic inflammation have not been fully elucidated …
[HTML][HTML] Haemostasis in cirrhosis: understanding destabilising factors during acute decompensation
A Zanetto, P Northup, L Roberts, M Senzolo - Journal of Hepatology, 2023 - Elsevier
Hospitalised patients with decompensated cirrhosis are in a rebalanced haemostatic state
due to a parallel decline in both pro-and anti-haemostatic pathways. However, this …
due to a parallel decline in both pro-and anti-haemostatic pathways. However, this …
[PDF][PDF] Impact of alcohol use disorder treatment on clinical outcomes among patients with cirrhosis
Background and Aims Despite the significant medical and economic consequences of
coexisting alcohol use disorder (AUD) in patients with cirrhosis, little is known about AUD …
coexisting alcohol use disorder (AUD) in patients with cirrhosis, little is known about AUD …
Rebalanced hemostasis in patients with liver disease: evidence and clinical consequences
T Lisman, RJ Porte - Blood, The Journal of the American …, 2010 - ashpublications.org
Patients with liver disease frequently acquire a complex disorder of hemostasis secondary to
their disease. Routine laboratory tests such as the prothrombin time and the platelet count …
their disease. Routine laboratory tests such as the prothrombin time and the platelet count …
Concepts and controversies in haemostasis and thrombosis associated with liver disease: Proceedings of the 7th International Coagulation in Liver Disease …
NM Intagliata, CK Argo, JG Stine… - Thrombosis and …, 2018 - thieme-connect.com
Patients with acute and chronic liver disease frequently acquire unique changes in
haemodynamic and haemostatic pathways that may result in life-threatening bleeding and …
haemodynamic and haemostatic pathways that may result in life-threatening bleeding and …
[PDF][PDF] Coagulation parameters and major bleeding in critically ill patients with cirrhosis
A Drolz, T Horvatits, K Roedl, K Rutter, K Staufer… - …, 2016 - Wiley Online Library
Disturbances of coagulation and hemostasis are common in patients with liver cirrhosis. The
typical laboratory pattern mimics disseminated intravascular coagulation (DIC). The aim of …
typical laboratory pattern mimics disseminated intravascular coagulation (DIC). The aim of …
Gut-liver axis in liver cirrhosis: How to manage leaky gut and endotoxemia
H Fukui - World journal of hepatology, 2015 - pmc.ncbi.nlm.nih.gov
A “leaky gut” may be the cutting edge for the passage of toxins, antigens or bacteria into the
body, and may play a pathogenic role in advanced liver cirrhosis and its complications …
body, and may play a pathogenic role in advanced liver cirrhosis and its complications …
Coagulation disorders in liver disease
L Amitrano, MA Guardascione… - Seminars in liver …, 2002 - thieme-connect.com
The liver plays a central role in the clotting process, and acute and chronic liver diseases are
invariably associated with coagulation disorders due to multiple causes: decreased …
invariably associated with coagulation disorders due to multiple causes: decreased …
Infection, coagulation, and variceal bleeding in cirrhosis
Bacterial infections in cirrhotic patients are common. There is a predisposition to intestinal
bacterial overgrowth, intestinal dysmotility, and increased intestinal permeability, all leading …
bacterial overgrowth, intestinal dysmotility, and increased intestinal permeability, all leading …
Thrombin-activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with increased plasma fibrinolysis
Background & Aims: The bleeding tendency of patients suffering from cirrhosis is in part
ascribed to accelerated fibrinolysis. In this study, the role of the recently discovered inhibitor …
ascribed to accelerated fibrinolysis. In this study, the role of the recently discovered inhibitor …