Bioactive materials are a kind of materials with unique bioactivities, which can change the
cellular behaviors and elicit biological responses from living tissues. Bioactive materials …

Therapeutic targeting of the immune system in cancer is now a clinical reality and marked
successes have been achieved, most notably through the use of checkpoint blockade …

Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …

In recent decades, as a subclass of biomaterials, biologically sensitive nanoparticles have
attracted increased scientific interest. Many of the demands for physiologically responsive …

Combined checkpoint blockade (eg, PD1/PD-L1) with traditional clinical therapies can be
hampered by side effects and low tumour-therapeutic outcome, hindering broad clinical …

T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …

Conspectus Nanomedicine holds significant potential to improve the efficacy of cancer
immunotherapy. Thus far, nanomedicines, ie, 1–100 (0) nm sized drug delivery systems …

Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …