White matter microstructure and cognitive decline in metabolic syndrome: a review of diffusion tensor imaging

FJ Alfaro, A Gavrieli, P Saade-Lemus, VA Lioutas… - Metabolism, 2018 - Elsevier
Metabolic syndrome is a cluster of cardiovascular risk factors defined by the presence of
abdominal obesity, glucose intolerance, hypertension and/or dyslipidemia. It is a major …

Connecting the dots between hypercholesterolemia and Alzheimer's disease: a potential mechanism based on 27-hydroxycholesterol

M Wu, Y Zhai, X Liang, W Chen, R Lin, L Ma… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common cause of dementia, is a complex and
multifactorial disease involving genetic and environmental factors, with …

High fat diet-induced obesity leads to depressive and anxiety-like behaviors in mice via AMPK/mTOR-mediated autophagy

Y Li, Y Cheng, Y Zhou, H Du, C Zhang, Z Zhao… - Experimental …, 2022 - Elsevier
Depression is one of the most common mental illnesses in modern society. In recent years,
several studies show that there are disturbances in lipid metabolism in depressed patients …

Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study

DM Lipnicki, SR Makkar, JD Crawford… - PLoS …, 2019 - journals.plos.org
Background With no effective treatments for cognitive decline or dementia, improving the
evidence base for modifiable risk factors is a research priority. This study investigated …

[HTML][HTML] Low levels of low-density lipoprotein cholesterol and cognitive decline

R Hua, Y Ma, C Li, B Zhong, W **e - Science Bulletin, 2021 - Elsevier
The relationship between low levels of serum low-density lipoprotein cholesterol (LDL-C)
and subsequent cognitive decline remains unclear. The present study aimed to evaluate the …

The association between midlife serum high-density lipoprotein and mild cognitive impairment and dementia after 19 years of follow-up

T Svensson, N Sawada, M Mimura, S Nozaki… - Translational …, 2019 - nature.com
A third of dementia cases could be attributable to modifiable risk-factors. Midlife high-density
lipoprotein cholesterol (HDL-C) is a measure which could help identify individuals at …

In Silico and In Vitro Analysis of Tacca Tubers (Tacca leontopetaloides) from Banyak Island, Aceh Singkil Regency, Indonesia, as Antihypercholesterolemia Agents

R Rachmawati, R Idroes, E Suhartono, NB Maulydia… - Molecules, 2022 - mdpi.com
Tacca leontopetaloides (T. leontopetaloides) contain a number of active compounds such as
flavonoids, tannins, phenolics, steroids, and alkaloids. The active compounds from plants …

Longitudinal and nonlinear relations of dietary and Serum cholesterol in midlife with cognitive decline: results from EMCOA study

Y An, X Zhang, Y Wang, Y Wang, W Liu, T Wang… - Molecular …, 2019 - Springer
Background Previous studies regarding the cholesterol-cognition relationship in midlife
have generated conflicting results. We thus investigated whether dietary and blood …

Age related prevalence of mild cognitive impairment in type 2 diabetes mellitus patients in the indian population and association of serum lipids with cognitive …

A Chakraborty, S Hegde, SK Praharaj… - Frontiers in …, 2021 - frontiersin.org
The magnitude of type 2 diabetes mellitus (T2DM) is ever-increasing in India, and at
present,~ 77 million people live with diabetes. Studies have established that T2DM …

[HTML][HTML] Impaired cholesterol metabolism, neurons, and neuropsychiatric disorders

SY Cheon - Experimental Neurobiology, 2023 - ncbi.nlm.nih.gov
Cholesterol metabolism plays an essential role in cellular functions (including as a
component of the plasma membrane, as an energy source, and in hormone production) …