Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer's disease

Y Zhang, Y Wang, C Shi, M Shen, F Lu - Translational neurodegeneration, 2021 - Springer
As the most common form of dementia, Alzheimer's disease (AD) is characterized by
progressive cognitive impairments and constitutes a major social burden. Currently, the …

[HTML][HTML] Optical coherence tomography in schizophrenia spectrum disorders: A systematic review and meta-analysis

W Shew, DJ Zhang, DB Menkes… - … Psychiatry Global Open …, 2024 - Elsevier
Background Inner retinal atrophy has been demonstrated in schizophrenia spectrum
disorder (SSD) using optical coherence tomography (OCT). This systematic review and meta …

Visual impairment and retinal and brain neurodegeneration: a population‐based study

D Garzone, RP Finger, MM Mauschitz… - Human Brain …, 2023 - Wiley Online Library
Visual impairment and retinal neurodegeneration are intrinsically connected and both have
been associated with cognitive impairment and brain atrophy, but the underlying …

Deep phenoty** and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

K **e, H Fuchs, E Scifo, D Liu, A Aziz… - Nature …, 2022 - nature.com
Current concepts regarding the biology of aging are primarily based on studies aimed at
identifying factors regulating lifespan. However, lifespan as a sole proxy measure for aging …

Association between accelerometer-derived physical activity measurements and brain structure: a population-based cohort study

FAU Fox, K Diers, H Lee, A Mayr, M Reuter… - Neurology, 2022 - neurology.org
Background and Objectives While there is growing evidence that physical activity promotes
neuronal health, studies examining the relation between physical activity and brain …

Retinal layer assessments as potential biomarkers for brain atrophy in the Rhineland Study

MM Mauschitz, V Lohner, A Koch, T Stöcker… - Scientific reports, 2022 - nature.com
Retinal assessments have been discussed as biomarkers for brain atrophy. However,
available studies did not investigate all retinal layers due to older technology, reported …

Retinal neurodegeneration as a potential biomarker of accelerated aging in schizophrenia spectrum disorders

BA Blose, A Lai, C Crosta, JL Thompson… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypotheses Several biological markers are believed to reflect
accelerated aging in schizophrenia spectrum disorders; however, retinal neural changes …

Markers and mechanisms of death in Drosophila

J Tower - Frontiers in Aging, 2023 - frontiersin.org
Parameters correlated with age and mortality in Drosophila melanogaster include
decreased negative geotaxis and centrophobism behaviors, decreased climbing and …

Neurovascular coupling unit dysfunction and dementia: Retinal measurements as tools to move towards population-based evidence

FCT van der Heide, TT van Sloten… - Frontiers in …, 2022 - frontiersin.org
Dysfunction of the neurovascular coupling unit may be an important contributor to dementia.
The neurovascular coupling unit comprises neuronal structures (eg astrocytes) and vascular …

The association of psychological well-being with sensory and cognitive function and neuronal health in aging adults

N Merten, AA Pinto, AJ Paulsen… - Journal of aging …, 2022 - journals.sagepub.com
Objectives Psychological well-being (PWB) may be a potential modifiable risk factor of age-
related diseases. We aimed to determine associations of PWB with sensorineural and …