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Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications
Q Zhong, X **ao, Y Qiu, Z Xu, C Chen, B Chong… - MedComm, 2023 - Wiley Online Library
Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …
[HTML][HTML] Advances in understanding N-glycosylation structure, function, and regulation in health and disease
S Esmail, MF Manolson - European Journal of Cell Biology, 2021 - Elsevier
N-linked glycosylation is a post-translational modification crucial for membrane protein
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …
Glycans and cancer: role of N-glycans in cancer biomarker, progression and metastasis, and therapeutics
N Taniguchi, Y Kizuka - Advances in cancer research, 2015 - Elsevier
Glycosylation is catalyzed by various glycosyltransferase enzymes which are mostly located
in the Golgi apparatus in cells. These enzymes glycosylate various complex carbohydrates …
in the Golgi apparatus in cells. These enzymes glycosylate various complex carbohydrates …
[HTML][HTML] Circulating proteins as diagnostic markers in gastric cancer
Gastric cancer (GC) is a highly malignant disease affecting humans worldwide and has a
poor prognosis. Most GC cases are detected at advanced stages due to the cancer lacking …
poor prognosis. Most GC cases are detected at advanced stages due to the cancer lacking …
The functional roles of protein glycosylation in human maternal–fetal crosstalk
BACKGROUND The establishment of maternal–fetal crosstalk is vital to a successful
pregnancy. Glycosylation is a post-translational modification in which glycans …
pregnancy. Glycosylation is a post-translational modification in which glycans …
Integrated glycoproteomic characterization of clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC), a common form of RCC, is responsible for the high
mortality rate of kidney cancer. Dysregulations of glycoproteins have been shown to …
mortality rate of kidney cancer. Dysregulations of glycoproteins have been shown to …
Altered glycosylation in cancer: molecular functions and therapeutic potential
X Xu, Q Peng, X Jiang, S Tan, W Yang… - Cancer …, 2024 - Wiley Online Library
Glycosylation, a key mode of protein modification in living organisms, is critical in regulating
various biological functions by influencing protein folding, transportation, and localization …
various biological functions by influencing protein folding, transportation, and localization …
Insight into structure evolution of carbon nitrides and its energy conversion as luminescence
H Zhang, J Zhang, W Chen, M Tao, X Meng… - Carbon …, 2024 - Wiley Online Library
A series of carbon nitride (CN) materials represented by graphitic carbon nitride (g‐C3N4)
have been widely used in bioimaging, biosensing, and other fields in recent years due to …
have been widely used in bioimaging, biosensing, and other fields in recent years due to …
Sensitive Electrochemical Aptamer Biosensor for Dynamic Cell Surface N-Glycan Evaluation Featuring Multivalent Recognition and Signal Amplification on a …
X Chen, Y Wang, Y Zhang, Z Chen, Y Liu… - Analytical …, 2014 - ACS Publications
We demonstrate a multivalent recognition and highly selective aptamer signal amplification
strategy for electrochemical cytosensing and dynamic cell surface N-glycan expression …
strategy for electrochemical cytosensing and dynamic cell surface N-glycan expression …
Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer
S Carvalho, TA Catarino, AM Dias, M Kato, A Almeida… - Oncogene, 2016 - nature.com
E-cadherin is a central molecule in the process of gastric carcinogenesis and its
posttranslational modifications by N-glycosylation have been described to induce a …
posttranslational modifications by N-glycosylation have been described to induce a …