Emerging applications of metabolomics in drug discovery and precision medicine

DS Wishart - Nature reviews Drug discovery, 2016 - nature.com
Metabolomics is an emerging'omics' science involving the comprehensive characterization
of metabolites and metabolism in biological systems. Recent advances in metabolomics …

Towards nutrition with precision: unlocking biomarkers as dietary assessment tools

C Cuparencu, T Bulmuş-Tüccar, J Stanstrup… - Nature …, 2024 - nature.com
Precision nutrition requires precise tools to monitor dietary habits. Yet current dietary
assessment instruments are subjective, limiting our understanding of the causal …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

[HTML][HTML] The food metabolome: a window over dietary exposure

A Scalbert, L Brennan, C Manach… - The American journal of …, 2014 - Elsevier
The food metabolome is defined as the part of the human metabolome directly derived from
the digestion and biotransformation of foods and their constituents. With> 25,000 …

Precision nutrition for prevention and management of type 2 diabetes

DD Wang, FB Hu - The lancet Diabetes & endocrinology, 2018 - thelancet.com
Precision nutrition aims to prevent and manage chronic diseases by tailoring dietary
interventions or recommendations to one or a combination of an individual's genetic …

Advances in dietary pattern analysis in nutritional epidemiology

CA Schulz, K Oluwagbemigun, U Nöthlings - European journal of nutrition, 2021 - Springer
Abstract Background and Purpose It used to be a common practice in the field of nutritional
epidemiology to analyze separate nutrients, foods, or food groups. However, in reality …

[HTML][HTML] Identifying biomarkers of dietary patterns by using metabolomics

MC Playdon, SC Moore, A Derkach, J Reedy… - The American journal of …, 2017 - Elsevier
Background: Healthy dietary patterns that conform to national dietary guidelines are related
to lower chronic disease incidence and longer life span. However, the precise mechanisms …

Validation of biomarkers of food intake—critical assessment of candidate biomarkers

LO Dragsted, Q Gao, A Scalbert, G Vergères… - Genes & nutrition, 2018 - Springer
Biomarkers of food intake (BFIs) are a promising tool for limiting misclassification in nutrition
research where more subjective dietary assessment instruments are used. They may also …

[HTML][HTML] Nutritional metabolomics and the classification of dietary biomarker candidates: a critical review

T Rafiq, SM Azab, KK Teo, L Thabane, SS Anand… - Advances in …, 2021 - Elsevier
Recent advances in metabolomics allow for more objective assessment of contemporary
food exposures, which have been proposed as an alternative or complement to self …

[HTML][HTML] Optimized analytical procedures for the untargeted metabolomic profiling of human urine and plasma by combining hydrophilic interaction (HILIC) and reverse …

K Contrepois, L Jiang, M Snyder - Molecular & Cellular Proteomics, 2015 - Elsevier
Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health
and disease and for providing insights into human physiology. Since human urine and …