A roadmap for metagenomic enzyme discovery

SL Robinson, J Piel, S Sunagawa - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Metagenomics has yielded massive amounts of sequencing data
offering a glimpse into the biosynthetic potential of the uncultivated microbial majority. While …

A crowdsourcing open platform for literature curation in UniProt

Y Wang, Q Wang, H Huang, W Huang, Y Chen… - PLoS …, 2021 - journals.plos.org
The UniProt knowledgebase is a public database for protein sequence and function,
covering the tree of life and over 220 million protein entries. Now, the whole community can …

Expasy, the Swiss Bioinformatics Resource Portal, as designed by its users

S Duvaud, C Gabella, F Lisacek… - Nucleic acids …, 2021 - academic.oup.com
Abstract The SIB Swiss Institute of Bioinformatics (https://www. sib. swiss) creates, maintains
and disseminates a portfolio of reliable and state-of-the-art bioinformatics services and …

UniProt: a worldwide hub of protein knowledge

UniProt Consortium - Nucleic acids research, 2019 - academic.oup.com
Abstract The UniProt Knowledgebase is a collection of sequences and annotations for over
120 million proteins across all branches of life. Detailed annotations extracted from the …

LitCovid: an open database of COVID-19 literature

Q Chen, A Allot, Z Lu - Nucleic acids research, 2021 - academic.oup.com
Since the outbreak of the current pandemic in 2020, there has been a rapid growth of
published articles on COVID-19 and SARS-CoV-2, with about 10 000 new articles added …

PubTator central: automated concept annotation for biomedical full text articles

CH Wei, A Allot, R Leaman, Z Lu - Nucleic acids research, 2019 - academic.oup.com
Abstract PubTator Central (https://www. ncbi. nlm. nih. gov/research/pubtator/) is a web
service for viewing and retrieving bioconcept annotations in full text biomedical articles …

Decoupling of respiration rates and abundance in marine prokaryoplankton

JH Munson-McGee, MR Lindsay, E Sintes, JM Brown… - Nature, 2022 - nature.com
The ocean–atmosphere exchange of CO2 largely depends on the balance between marine
microbial photosynthesis and respiration. Despite vast taxonomic and metabolic diversity …

Reverse screening methods to search for the protein targets of chemopreventive compounds

H Huang, G Zhang, Y Zhou, C Lin, S Chen, Y Lin… - Frontiers in …, 2018 - frontiersin.org
This article is a systematic review of reverse screening methods used to search for the
protein targets of chemopreventive compounds or drugs. Typical chemopreventive …

LitSuggest: a web-based system for literature recommendation and curation using machine learning

A Allot, K Lee, Q Chen, L Luo, Z Lu - Nucleic acids research, 2021 - academic.oup.com
Searching and reading relevant literature is a routine practice in biomedical research.
However, it is challenging for a user to design optimal search queries using all the keywords …

[HTML][HTML] Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer

D Huang, S Chowdhury, H Wang, SR Savage… - Cell Reports …, 2021 - cell.com
Resistance to platinum compounds is a major determinant of patient survival in high-grade
serous ovarian cancer (HGSOC). To understand mechanisms of platinum resistance and …