Emerging ROS-modulating technologies for augmentation of the wound healing process

S Polaka, P Katare, B Pawar, N Vasdev, T Gupta… - ACS …, 2022‏ - ACS Publications
Reactive oxygen species (ROS) is considered a double-edged sword. The slightly elevated
level of ROS helps in wound healing by inhibiting microbial infection. In contrast, excessive …

Transition from inflammation to proliferation: a critical step during wound healing

NX Landén, D Li, M Ståhle - Cellular and Molecular Life Sciences, 2016‏ - Springer
The ability to rapidly restore the integrity of a broken skin barrier is critical and is the ultimate
goal of therapies for hard-to-heal-ulcers. Unfortunately effective treatments to enhance …

The role of chemokines in wound healing

A Ridiandries, JTM Tan, CA Bursill - International journal of molecular …, 2018‏ - mdpi.com
Wound healing is a multistep process with four overlap** but distinct stages: hemostasis,
inflammation, proliferation, and remodeling. An alteration at any stage may lead to the …

[HTML][HTML] Androgen-induced immunosuppression

MR Gubbels Bupp, TN Jorgensen - Frontiers in immunology, 2018‏ - frontiersin.org
In addition to determining biological sex, sex hormones are known to influence health and
disease via regulation of immune cell activities and modulation of target-organ susceptibility …

Sexual dimorphism in cancer

A Clocchiatti, E Cora, Y Zhang, GP Dotto - Nature Reviews Cancer, 2016‏ - nature.com
The incidence of many types of cancer arising in organs with non-reproductive functions is
significantly higher in male populations than in female populations, with associated …

Aging and wound healing

A Gosain, LA DiPietro - World journal of surgery, 2004‏ - Springer
Impaired wound healing in the elderly presents a major clinical and economic problem. With
the aging population growing in both number and percentage, the importance of …

Oxidative stress in normal and impaired wound repair

M Schäfer, S Werner - Pharmacological research, 2008‏ - Elsevier
A large percentage of the population suffers from wound healing abnormalities, in particular
aged individuals, patients with diabetes, and those treated with immunosuppressive drugs …

Sex hormones regulate innate immune cells and promote sex differences in respiratory virus infection

S Kadel, S Kovats - Frontiers in immunology, 2018‏ - frontiersin.org
Sex differences in the incidence and severity of respiratory virus infection are widely
documented in humans and murine models and correlate with sex biases in numbers and/or …

Menopause and the skin: old favorites and new innovations in cosmeceuticals for estrogen-deficient skin

ED Lephart, F Naftolin - Dermatology and therapy, 2021‏ - Springer
Estrogen is a pivotal signaling molecule; its production is regulated by the expression of the
aromatase (CYP19A1) gene from ovarian and peripheral tissue sites, and it is transmitted …

Androgens and androgen receptor action in skin and hair follicles

JM Ceruti, GJ Leirós, ME Balañá - Molecular and cellular endocrinology, 2018‏ - Elsevier
Beyond sexual functions, androgens exert their action in skin physiology and
pathophysiology. Skin cells are able to synthesize most active androgens from gonadal or …