Analytical approaches for determination of COVID-19 candidate drugs in human biological matrices

R Mahdavi, Z Talebpour - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Since the outbreak of the COVID-19 pandemic, the use of antiviral and other available drugs
has been considered to combat or reduce the clinical symptoms of patients. In this regard, it …

Highly sensitive high‐performance thin‐layer chromatography method for the simultaneous determination of molnupiravir, favipiravir, and ritonavir in pure forms and …

RE Saraya, SE Deeb, BI Salman… - Journal of separation …, 2022 - Wiley Online Library
Favipiravir, molnupiravir, and ritonavir have been recently approved as the first oral
antivirals for treatment of SARS‐CoV‐2 viral infections. Their combination was reported in …

Green micellar solvent-free HPLC and spectrofluorimetric determination of favipiravir as one of COVID-19 antiviral regimens

IE Mikhail, H Elmansi, F Belal, AE Ibrahim - Microchemical Journal, 2021 - Elsevier
Quality control (QC) of pharmaceutical products requires fast, sensitive as well as economic
methodologies in order to provide high through output at low cost which are the main …

[HTML][HTML] Modified GAPI (MoGAPI) tool and software for the assessment of method greenness: case studies and applications

FR Mansour, J Płotka-Wasylka, M Locatelli - Analytica, 2024 - mdpi.com
The green analytical procedure index (GAPI) has been widely used to assess the greenness
of different steps in analytical methodology. In the GAPI index, the different stages of the …

First electrochemical evaluation of favipiravir used as an antiviral option in the treatment of COVID-19: A study of its enhanced voltammetric determination in cationic …

S Allahverdiyeva, O Yunusoğlu, Y Yardım… - Analytica Chimica Acta, 2021 - Elsevier
Favipiravir, a promising antiviral agent, is undergoing clinical trials for the potential treatment
of the novel coronavirus disease 2019 (COVID-19). This is the first report for the …

Two green micellar HPLC and mathematically assisted UV spectroscopic methods for the simultaneous determination of molnupiravir and favipiravir as a novel …

YA Sharaf, S El Deeb, AE Ibrahim, A Al-Harrasi… - Molecules, 2022 - mdpi.com
Following the spread of the COVID-19 pandemic crisis, a race was initiated to find a
successful regimen for postinfections. Among those trials, a recent study declared the …

A novel stability-indicating HPLC-DAD method for determination of favipiravir, a potential antiviral drug for COVID-19 treatment; application to degradation kinetic …

HM Marzouk, MR Rezk, AS Gouda… - Microchemical …, 2022 - Elsevier
Modern pharmaceutical analysis is paying a lot of attention to the stability of novel drug
formulations as well as establishment of suitable stability-indicating approaches. In the …

Recent application of green analytical chemistry: eco-friendly approaches for pharmaceutical analysis

M Mehta, D Mehta, R Mashru - Future Journal of Pharmaceutical Sciences, 2024 - Springer
Background The substantially operated analytical instruments dealing in the area of
analytical chemistry are traditional methods like high-performance liquid chromatography …

Voltammetric sensor based on bimetallic nanocomposite for determination of favipiravir as an antiviral drug

M Mehmandoust, Y Khoshnavaz, M Tuzen, N Erk - Microchimica Acta, 2021 - Springer
A novel and sensitive voltammetric nanosensor was developed for the first time for trace
level monitoring of favipiravir based on gold/silver core–shell nanoparticles (Au@ Ag …

A novel LC-MS/MS method for determination of the potential antiviral candidate favipiravir for the emergency treatment of SARS-CoV-2 virus in human plasma …

MI Morsy, EG Nouman, YM Abdallah… - … of pharmaceutical and …, 2021 - Elsevier
A novel, fast and sensitive LC–MS/MS method was developed and validated for the
bioanalysis of the antiviral agent favipiravir (FAV); a promising candidate for treatment of …