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[HTML][HTML] Multiple neuronal populations control the eating behavior in Hydra and are responsive to microbial signals
C Giez, D Pinkle, Y Giencke, J Wittlieb, E Herbst… - Current Biology, 2023 - cell.com
Although recent studies indicate the impact of microbes on the central nervous systems and
behavior, it remains unclear how the relationship between the functionality of the nervous …
behavior, it remains unclear how the relationship between the functionality of the nervous …
[HTML][HTML] Satiety controls behavior in Hydra through an interplay of pre-enteric and central nervous system-like neuron populations
C Giez, C Noack, E Sakib, LM Hofacker, U Repnik… - Cell Reports, 2024 - cell.com
Hunger and satiety can have an influence on decision-making, sensory processing, and
motor behavior by altering the internal state of the brain. This process necessitates the …
motor behavior by altering the internal state of the brain. This process necessitates the …
Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1
Despite the unique ability of pioneer factors (PFs) to target nucleosomal sites in closed
chromatin, they only bind a small fraction of their genomic motifs. The underlying mechanism …
chromatin, they only bind a small fraction of their genomic motifs. The underlying mechanism …
[HTML][HTML] Pressurized Hot Water Extraction of Mangosteen Pericarp and Its Associated Molecular Signatures in Endothelial Cells
The mangosteen (Garcinia mangostana L.) pericarp is known to be rich in potent bioactive
phytochemical compounds such as xanthones, which possess pharmacologically important …
phytochemical compounds such as xanthones, which possess pharmacologically important …
The amyloid precursor protein regulates synaptic transmission at medial perforant path synapses
The perforant path provides the primary cortical excitatory input to the hippocampus.
Because of its important role in information processing and coding, entorhinal projections to …
Because of its important role in information processing and coding, entorhinal projections to …
[HTML][HTML] Multiomics with Evolutionary Computation to Identify Molecular and Module Biomarkers for Early Diagnosis and Treatment of Complex Disease
H Cheng, M Liang, Y Gao, W Zhao, WF Guo - Genes, 2025 - mdpi.com
It is important to identify disease biomarkers (DBs) for early diagnosis and treatment of
complex diseases in personalized medicine. However, existing methods integrating …
complex diseases in personalized medicine. However, existing methods integrating …
Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms
SG Martins, V Ribeiro, C Melo… - Life Science …, 2024 - life-science-alliance.org
LAMA2, coding for the laminin-α2 chain, is a crucial ECM component, particularly abundant
in skeletal muscle. Mutations in LAMA2 trigger the often-lethal LAMA2-congenital muscular …
in skeletal muscle. Mutations in LAMA2 trigger the often-lethal LAMA2-congenital muscular …
Upregulation of inhibitor of DNA binding 1 and 3 is important for efficient thermogenic response in human adipocytes
Brown and beige adipocytes can be activated by β-adrenergic agonist via cAMP-dependent
signaling. Performing RNA-sequencing analysis in human cervical area-derived adipocytes …
signaling. Performing RNA-sequencing analysis in human cervical area-derived adipocytes …
Unravelling the role of long non-coding RNAs in modulating the Hedgehog pathway in cancer
Cancer is a multifactorial pathological condition characterized by uncontrolled cellular
proliferation, genomic instability, and evasion of regulatory mechanisms. It arises from the …
proliferation, genomic instability, and evasion of regulatory mechanisms. It arises from the …
Application of transcriptomic profiling to investigate the toxicity mechanisms caused by dietary exposure of nanoplastics in fish
Nowadays, nanoplastics (NPs) are one of the main concerns regarding plastic pollution. The
increasing presence of plastic particles, fibers and fragments in the marine environment …
increasing presence of plastic particles, fibers and fragments in the marine environment …