Unveiling the cancer risk nexus of the steatotic liver

J Kim, E Seki - Trends in Endocrinology & Metabolism, 2024 - cell.com
Steatotic liver, characterized by the accumulation of fat in the liver, poses significant health
risks including metabolic dysfunction-associated steatotic liver disease (MASLD) and an …

[HTML][HTML] Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of hepatocellular carcinoma (HCC)

Y Pan, Y Li, H Fan, H Cui, Z Chen, Y Wang… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) holds a prominent position among global cancer types.
Classically, HCC manifests in individuals with a genetic predisposition when they encounter …

Crosstalk between epigenetics and metabolic reprogramming in metabolic dysfunction-associated steatotic liver disease-induced hepatocellular carcinoma: a new …

A Li, R Wang, Y Zhao, P Zhao, J Yang - Metabolites, 2024 - mdpi.com
Epigenetic and metabolic reprogramming alterations are two important features of tumors,
and their reversible, spatial, and temporal regulation is a distinctive hallmark of …

MicroRNAs in metabolic dysfunction‐associated diseases: Pathogenesis and therapeutic opportunities

N Ma, J Tan, Y Chen, L Yang, M Li, Y He - The FASEB Journal, 2024 - Wiley Online Library
Metabolic dysfunction‐associated diseases often refer to various diseases caused by
metabolic problems such as glucose and lipid metabolism disorders. With the improvement …

A comprehensive review of miR-21 in liver disease: Big impact of little things

X Xue, Y Li, Y Yao, S Zhang, C Peng, Y Li - International …, 2024 - Elsevier
Abstract microRNAs (miRNAs), a class of non-coding RNA with 20–24 nucleotides, are
defined as the powerful regulators for gene expression. miR-21 is a multifunctional miRNA …

Absolute Quantification of Selected microRNAs Expression in Endometrial Cancer by Digital PCR

A Bogaczyk, N Potocka, S Paszek, M Skrzypa… - International Journal of …, 2024 - mdpi.com
MicroRNAs (miRNA) are involved in the process of carcinogenesis, including the
development of endometrial cancer (EC). This study aimed to investigate the association …

miR‐21p‐5p coordinates biological pathways to promote MASLD progression.

P Aspichueta, MB Zeisel - Liver International, 2023 - search.ebscohost.com
Abstract MiR-21p-5p coordinates biological pathways to promote MASLD progression
Keywords: hepatocellular carcinoma (HCC); metabolic dysfunction-associated …

Tea leaf exosome-like nanoparticles (TELNs) improve oleic acid-induced lipid metabolism by regulating miRNAs in HepG-2 cells

X Lei, H Li, S Chen, B Li, H **a, J Li, F Guan… - Bioresources and …, 2025 - Springer
Tea is a widely consumed beverage globally, but the tea industry faces a significant waste
management challenge. In this study, we developed tea leaf exosome-like nanoparticles …

Artificial intelligence-based evaluation of prognosis in cirrhosis

Y Zhai, D Hai, L Zeng, C Lin, X Tan, Z Mo, Q Tao… - Journal of Translational …, 2024 - Springer
Cirrhosis represents a significant global health challenge, characterized by high morbidity
and mortality rates that severely impact human health. Timely and precise prognostic …

Aurora-A promotes lenvatinib resistance experimentally through hsa-circ-0058046/miR-424-5p/FGFR1 axis in hepatocellular carcinoma

M Abudoureyimu, N Sun, W Chen… - International …, 2025 - journals.sagepub.com
Objective: This study aimed to investigate whether the dysregulation of Aurora-A is involved
in lenvatinib resistance in hepatocellular carcinoma. Methods: Bioinformatics tools and drug …