Calcium signalling has long been implicated in bipolar disorder, especially by reports of
altered intracellular calcium ion concentrations ([Ca2+]). However, the evidence has not …

Anomalies in neuronal cell architecture, in particular dendritic complexity and synaptic
density changes, are widely observed in the brains of subjects with schizophrenia or mood …

Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

The olfactory mucosa (OM) is a unique source of regenerative neural tissue that is readily
obtainable from living human subjects and thus affords opportunities for the study of …

Bipolar disorder (BD) and schizophrenia are psychiatric disorders that manifest unusual
mental, behavioral, and emotional patterns leading to suffering and disability. These …

The long lapse between the presumptive origin of schizophrenia (SCZ) during early
development and its diagnosis in late adolescence has hindered the study of crucial …

Smell loss has caught public attention during the recent COVID-19 pandemic. Research on
olfactory function in health and disease gains new momentum. Smell deficits have long …

Background There is an emerging interest in the use of cellular models to study psychiatric
disorders. We have systematically reviewed the application of cellular models to understand …

Schizophrenia (SZ) is a multifactorial disorder characterized by volume reduction in gray
and white matter, oxidative stress, neuroinflammation, altered neurotransmission, as well as …

The olfactory epithelium retains the capacity for lifelong neurogenesis and regeneration,
because of the presence of neural stem cells and progenitors. Thus, both mature neurons …