Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad
prospects for human therapeutic model development and livestock breeding. Despite …

As a natural extension of link prediction on graphs, hyperlink prediction aims for the
inference of missing hyperlinks in hypergraphs, where a hyperlink can connect more than …

Folliculogenesis is a complex biological process involving a central oocyte and its
surrounding somatic cells. Three-dimensional chromatin architecture is an important …

Chromatin architecture, a key regulator of gene expression, can be inferred using chromatin
contact data from chromosome conformation capture, or Hi-C. However, classical Hi-C does …

Chickens are the most abundant agricultural animals globally, with controlling abdominal fat
deposition being a key objective in poultry breeding. While GWAS can identify genetic …

Liver development is a complex process that is regulated by a series of signaling pathways.
Three-dimensional (3D) chromatin architecture plays an important role in transcriptional …

Background Development of hematopoietic stem and progenitor cells (HSPC) is a multi-
staged complex process that conserved between zebrafish and mammals. Understanding …

Spermatogonial stem cells (SSCs) are able to undergo both self-renewal and differentiation.
Unlike self-renewal, which replenishes the SSC and progenitor pool, differentiation is an …

Every human somatic cell inherits a maternal and a paternal genome, which work together
to give rise to cellular phenotypes. However, the allele-specific relationship between gene …

The development of skeletal muscle are complicated processes involving genes responsible
for proper muscle morphology, contractility, cell proliferation, differentiation, interactions …