Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines

G Lazzari, P Couvreur, S Mura - Polymer Chemistry, 2017 - pubs.rsc.org
The application of nanotechnology to medicine, usually termed nanomedicine, has given a
crucial impulse to the design of various drug-loaded nanocarriers driven by the aim to …

Combination of microtubule targeting agents with other antineoplastics for cancer treatment

T Liang, L Lu, X Song, J Qi, J Wang - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Microtubule targeting agents (MTAs) have attracted extensive attention for cancer treatment.
However, their clinical efficacies are limited by intolerable toxicities, inadequate efficacy and …

Autophagy-dependent apoptosis induced by apoferritin–Cu (II) nanoparticles in multidrug-resistant colon cancer cells

K **ong, Y Zhou, J Karges, K Du, J Shen… - … Applied Materials & …, 2021 - ACS Publications
Chemotherapy continues to be the most commonly applied strategy for cancer. Despite the
impressive clinical success obtained with several drugs, increasing numbers of (multi) drug …

Design Strategies of Tumor‐Targeted Delivery Systems Based on 2D Nanomaterials

L Ding, M Liang, C Li, X Ji, J Zhang, W **e… - Small …, 2022 - Wiley Online Library
Conventional chemotherapy and radiotherapy are nonselective and nonspecific for cell
killing, causing serious side effects and threatening the lives of patients. It is of great …

Adapting and remolding: orchestrating tumor microenvironment normalization with photodynamic therapy by size transformable nanoframeworks

T Liang, B Zhang, Z **ng, Y Dong, H Xu… - Angewandte …, 2021 - Wiley Online Library
Abnormal tumor microenvironment (TME) facilitates tumor proliferation and metastasis and
establishes physiological barriers for effective transport of therapeutics inside the tumor …

[HTML][HTML] Nanostructures for site-specific delivery of oxaliplatin cancer therapy: Versatile nanoplatforms in synergistic cancer therapy

M Bagheri, MA Zandieh, M Daryab, SS Samaei… - Translational …, 2024 - Elsevier
As a clinically approved treatment strategy, chemotherapy-mediated tumor suppression has
been compromised, and in spite of introducing various kinds of anticancer drugs, cancer …

Co-encapsulation of hydrophilic and hydrophobic drugs into human H chain ferritin nanocarrier enhances antitumor efficacy

C Ning, Y Dong, K Yang, X Li, F Wang… - … Biomaterials Science & …, 2023 - ACS Publications
The biocompatible protein nanocarrier with homogeneous particle size is a promising
candidate material for the delivery of targeted drugs to tumors. Doxorubicin (DOX) is a …

Amphiphilic graphene quantum dots as self‐targeted fluorescence probes for cell nucleus imaging

L Wang, B Wu, W Li, S Wang, Z Li, M Li… - Advanced …, 2018 - Wiley Online Library
Herein, a one‐step solvothermal strategy to synthesize amphiphilic, highly fluorescent
graphene quantum dots (GQDs) as nucleus‐targeted fluorescence probes is reported. The …

Self-assembled viral nanoparticles as targeted anticancer vehicles

Y Wu, J Li, HJ Shin - Biotechnology and Bioprocess Engineering, 2021 - Springer
Viral nanoparticles (VNPs) comprise a variety of mammalian viruses, plant viruses, and
bacteriophages, that have been adopted as building blocks and supra-molecular templates …

Apoferritin nanocage for brain targeted doxorubicin delivery

Z Chen, M Zhai, X **e, Y Zhang, S Ma, Z Li… - Molecular …, 2017 - ACS Publications
An ideal brain-targeted nanocarrier must be sufficiently potent to penetrate the blood–brain
barrier (BBB) and sufficiently competent to target the cells of interest with adequate …