Obesity and cancer: existing and new hypotheses for a causal connection

TW Stone, M McPherson, LG Darlington - EBioMedicine, 2018 - thelancet.com
Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of
dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly …

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

H Maeda, J Wu, T Sawa, Y Matsumura… - Journal of controlled …, 2000 - Elsevier
Most solid tumors possess unique pathophysiological characteristics that are not observed
in normal tissues or organs, such as extensive angiogenesis and hence hypervasculature …

Grain legume proteins and nutraceutical properties

M Duranti - Fitoterapia, 2006 - Elsevier
Grain legumes are a valuable source of food proteins. Their exploitation is expected to grow
in relation of a growing world's food needs. Moreover, it is currently taking place a …

Protection against ionizing radiation by antioxidant nutrients and phytochemicals

JF Weiss, MR Landauer - Toxicology, 2003 - Elsevier
The potential of antioxidants to reduce the cellular damage induced by ionizing radiation
has been studied in animal models for more than 50 years. The application of antioxidant …

Protease inhibitors from plants as therapeutic agents-a review

MS Cid-Gallegos, LJ Corzo-Ríos… - Plant Foods for Human …, 2022 - Springer
Plant-based diets are a great source of protease inhibitors (PIs). Two of the most well-known
families of PIs are Bowman-Birk inhibitors (BBI) and Kunitz-type inhibitors (KTI). The first …

Antitumoral activity of snake venom proteins: new trends in cancer therapy

LA Calderon, JC Sobrinho, KD Zaqueo… - BioMed research …, 2014 - Wiley Online Library
For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …

[HTML][HTML] The Bowman-Birk inhibitor from soybeans as an anticarcinogenic agent

AR Kennedy - The American journal of clinical nutrition, 1998 - Elsevier
Certain protease inhibitors are effective at preventing or suppressing carcinogen-induced
transformation in vitro and carcinogenesis in animal model systems. One protease inhibitor …

Protease inhibitors from plants with antimicrobial activity

JY Kim, SC Park, I Hwang, H Cheong, JW Nah… - International journal of …, 2009 - mdpi.com
Antimicrobial proteins (peptides) are known to play important roles in the innate host
defense mechanisms of most living organisms, including plants, insects, amphibians and …

Biological effects of space radiation and development of effective countermeasures

AR Kennedy - Life sciences in space research, 2014 - Elsevier
As part of a program to assess the adverse biological effects expected from astronauts'
exposure to space radiation, numerous different biological effects relating to astronauts' …

'Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents

F Tosetti, N Ferrari, S De Flora, A Albini - The FASEB Journal, 2002 - Wiley Online Library
The potential to block tumor growth by inhibition of the neoangiogenic process represents
an intriguing approach to the treatment of solid tumors. The high proliferation rate in the …