Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Abstract N 6-methyladenosine (m6A), the most prevalent mRNA modification, has an
important function in diverse biological processes. However, the involvement of m6A in …

Macrophages become activated initiating innate immune responses. Depending on the
signals, macrophages obtain an array of activation phenotypes, described by the broad …

Background Macrophages are heterogenous phagocytic cells with an important role in the
innate immunity. They are, also, significant contributors in the adaptive immune system …

Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …

Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …

Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on
multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, but this …

As the first line of defence in the lung, alveolar macrophage contributes to maintaining lung
immune homoeostasis. Characterized by the heterogeneity and plasticity, macrophages …

Macrophages are crucial components of the immune system and play a critical role in the
initial defense against pathogens. They are highly heterogeneous and plastic and can be …