Regulatory RNAs in virulence and host‐microbe interactions

AJ Westermann - Regulating with RNA in Bacteria and Archaea, 2018 - Wiley Online Library
Infectious diseases caused by bacterial pathogens still constitute one of the major human
health threats (1). Within the host body, pathogenic bacteria face a wide variety of hostile …

Gre factors help Salmonella adapt to oxidative stress by improving transcription elongation and fidelity of metabolic genes

S Kant, JKA Till, L Liu, A Margolis, S Uppalapati… - PLoS …, 2023 - journals.plos.org
Detoxification, scavenging, and repair systems embody the archetypical antioxidant
defenses of prokaryotic and eukaryotic cells. Metabolic rewiring also aids with the …

StpA and Hha stimulate pausing by RNA polymerase by promoting DNA–DNA bridging of H-NS filaments

BA Boudreau, DR Hron, L Qin… - Nucleic acids …, 2018 - academic.oup.com
In enterobacteria, AT-rich horizontally acquired genes, including virulence genes, are
silenced through the actions of at least three nucleoid-associated proteins (NAPs): H-NS …

TriPepSVM: de novo prediction of RNA-binding proteins based on short amino acid motifs

A Bressin, R Schulte-Sasse, D Figini… - Nucleic acids …, 2019 - academic.oup.com
In recent years, hundreds of novel RNA-binding proteins (RBPs) have been identified,
leading to the discovery of novel RNA-binding domains. Furthermore, unstructured or …

Comparison of Salmonella enterica serovars Typhi and Typhimurium reveals typhoidal serovar-specific responses to bile

R Johnson, M Ravenhall, D Pickard… - Infection and …, 2018 - Am Soc Microbiol
Salmonella enterica serovars Typhi and Typhimurium cause typhoid fever and
gastroenteritis, respectively. A unique feature of typhoid infection is asymptomatic carriage …

CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level

Y El Mouali, T Gaviria-Cantin… - PLoS …, 2018 - journals.plos.org
Invasion of epithelial cells by Salmonella enterica requires expression of genes located in
the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated …

The Small RNA PinT Contributes to PhoP-Mediated Regulation of the Salmonella Pathogenicity Island 1 Type III Secretion System in Salmonella enterica Serovar …

K Kim, AD Palmer, CK Vanderpool… - Journal of …, 2019 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium induces inflammatory diarrhea and bacterial
uptake into intestinal epithelial cells using the Salmonella pathogenicity island 1 (SPI1) type …

Small RNAs Activate Salmonella Pathogenicity Island 1 by Modulating mRNA Stability through the hilD mRNA 3′ Untranslated Region

SZ Abdulla, K Kim, MS Azam, YA Golubeva… - Journal of …, 2023 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium is an enteric pathogen associated with foodborne
disease. Salmonella invades the intestinal epithelium using a type three secretion system …

An incoherent feedforward loop formed by SirA/BarA, HilE and HilD is involved in controlling the growth cost of virulence factor expression by Salmonella …

D Pérez-Morales, J Nava-Galeana… - PLoS …, 2021 - journals.plos.org
An intricate regulatory network controls the expression of Salmonella virulence genes. The
transcriptional regulator HilD plays a central role in this network by controlling the …

3′ untranslated regions: regulation at the end of the road

Y El Mouali, C Balsalobre - Current genetics, 2019 - Springer
Post-transcriptional gene regulation in bacteria plays a major role in the adaptation of
bacterial cells to the changing conditions encountered in the environment. In bacteria, most …