Iatrogenic vascular air embolism is a relatively infrequent event but is associated with
significant morbidity and mortality. These emboli can arise in many clinical settings such as …

Over the past forty years, animal models of focal cerebral ischaemia have allowed us to
identify the critical cerebral blood flow thresholds responsible for irreversible cell death …

We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement
of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal …

Background and Purpose—Recanalization of the occluded artery is a primary goal in stroke
treatment. Unfortunately, endovascular treatment is not always available, and tPA (tissue …

Tissue plasminogen activator (tPA) is the only FDA approved thrombolytic drug for acute
ischemic stroke but concerns regarding its limitations remain. Here, we developed a new …

Rapid vascular recanalization forms the basis for successful treatment of cerebral ischemia.
Currently, tissue plasminogen activator (t-PA) is the only approved thrombolytic drug for …

Background: Platelet cross-linking during arterial thrombosis involves von Willebrand Factor
(VWF) multimers. Therefore, proteolysis of VWF appears promising to disaggregate platelet …

Lead exposure is a global public health safety issue that severely disrupts brain
development and causes damage to the nervous system in early life. Probiotics and gut …

Laser speckle contrast imaging (LSCI) is a rapidly develo** technology broadly applied
for the full-field characterization of tissue perfusion. Over the recent years, significant …

Laser speckle contrast imaging (LSCI) is a real-time full-field non-invasive technique, which
is broadly applied to visualize blood flow in biomedical applications. In its foundation is the …