Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives

FI Milagro, ML Mansego, C De Miguel… - Molecular aspects of …, 2013 - Elsevier
Nutritional factors play a life-long role in human health. Indeed, there is growing evidence
that one of the mechanisms by which nutrients and bioactive compounds affect metabolic …

[HTML][HTML] Improvements in metabolic health with consumption of ellagic acid and subsequent conversion into urolithins: evidence and mechanisms

I Kang, T Buckner, NF Shay, L Gu, S Chung - Advances in nutrition, 2016 - Elsevier
Ellagic acid (EA) is a naturally occurring polyphenol found in some fruits and nuts, including
berries, pomegranates, grapes, and walnuts. EA has been investigated extensively because …

Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss

HPV Rupasinghe, S Sekhon-Loodu, T Mantso… - Pharmacology & …, 2016 - Elsevier
Excessive accumulation of fat as the result of more energy intake and less energy
expenditure is known as obesity. Lipids are essential components in the human body and …

Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes

WV Berghe - Pharmacological research, 2012 - Elsevier
Cancer, as one of the non-communicable diseases, remains one of the leading causes of
death around the world. Recently, epigenetic changes in DNA methylation patterns at CpG …

Cancer chemoprevention and nutri-epigenetics: state of the art and future challenges

C Gerhauser - Natural products in cancer prevention and therapy, 2013 - Springer
The term “epigenetics” refers to modifications in gene expression caused by heritable, but
potentially reversible, changes in DNA methylation and chromatin structure. Epigenetic …

Genome‐wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

J Delgado‐Calle, AF Fernández, J Sainz… - Arthritis & …, 2013 - Wiley Online Library
Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …

Therapeutic perspectives of epigenetically active nutrients

M Remely, L Lovrecic, AL De La Garza… - British journal of …, 2015 - Wiley Online Library
Many nutrients are known for a wide range of activities in prevention and alleviation of
various diseases. Recently, their potential role in regulating human health through effects on …

The role of isoflavones in type 2 diabetes prevention and treatment—A narrative review

A Kuryłowicz - International Journal of Molecular Sciences, 2020 - mdpi.com
Given the growing number of type 2 diabetic individuals and the substantial social and
financial costs associated with diabetes management, every effort should be made to …

Epigenetics of obesity

A Lopomo, E Burgio, L Migliore - Progress in molecular biology and …, 2016 - Elsevier
Obesity is a metabolic disease, which is becoming an epidemic health problem: it has been
recently defined in terms of Global Pandemic. Over the years, the approaches through …

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression

LJ Buro-Auriemma, J Salit, NR Hackett… - Human molecular …, 2013 - academic.oup.com
The small airway epithelium (SAE), the first site of smoking-induced lung pathology, exhibits
genome-wide changes in gene expression in response to cigarette smoking. Based on the …