T cells for viral infections after allogeneic hematopoietic stem cell transplant

CM Bollard, HE Heslop - Blood, The Journal of the American …, 2016 - ashpublications.org
Despite recent advances in the field of allogeneic hematopoietic stem cell transplantation
(HSCT), viral infections are still a major complication during the period of immune …

Strategies of adoptive T-cell transfer to treat refractory viral infections post allogeneic stem cell transplantation

T Kaeuferle, R Krauss, F Blaeschke, S Willier… - Journal of hematology & …, 2019 - Springer
Background Allogeneic hematopoietic stem cell transplantation (HSCT) can expose patients
to a transient but marked immunosuppression, during which viral infections are an important …

Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II …

MD Keller, PJ Hanley, YY Chi, P Aguayo-Hiraldo… - Nature …, 2024 - nature.com
Viral infections remain a major risk in immunocompromised pediatric patients, and virus-
specific T cell (VST) therapy has been successful for treatment of refractory viral infections in …

Adoptive transfer of Epstein-Barr virus (EBV) nuclear antigen 1–specific T cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic …

V Icheva, S Kayser, D Wolff, S Tuve… - Journal of clinical …, 2013 - ascopubs.org
Purpose Reactivation of Epstein-Barr virus (EBV) after allogeneic stem-cell transplantation
(SCT) can lead to severe life-threatening infections and trigger post-transplantation …

T-cell therapy in the treatment of post-transplant lymphoproliferative disease

CM Bollard, CM Rooney, HE Heslop - Nature reviews Clinical oncology, 2012 - nature.com
Post-transplant lymphoproliferative diseases (PTLD) associated with Epstein-Barr virus
(EBV) infection often develop after organ and haematopoietic stem-cell transplantation …

Post-transplant lymphoproliferative disorders

VR Dharnidharka, AC Webster, OM Martinez… - Nature reviews Disease …, 2016 - nature.com
Post-transplant lymphoproliferative disorders (PTLDs) are a group of conditions that involve
uncontrolled proliferation of lymphoid cells as a consequence of extrinsic …

Risk factors for Epstein-Barr virus-related post-transplant lymphoproliferative disease after allogeneic hematopoietic stem cell transplantation

M Uhlin, H Wikell, M Sundin, O Blennow… - …, 2014 - pmc.ncbi.nlm.nih.gov
Allogeneic hematopoietic stem cell transplantation is a successful treatment for hematologic
malignancies and a variety of genetic and metabolic disorders. In the period following stem …

Immunotherapy against cancer-related viruses

H Tashiro, MK Brenner - Cell research, 2017 - nature.com
Approximately 12% of all cancers worldwide are associated with viral infections. To date,
eight viruses have been shown to contribute to the development of human cancers …

EBV-induced post transplant lymphoproliferative disorders: a persisting challenge in allogeneic hematopoetic SCT

L Rasche, M Kapp, H Einsele, S Mielke - Bone marrow transplantation, 2014 - nature.com
EBV-induced post transplantation lymphoproliferative disorder (EBV-PTLD) is a life-
threatening complication after allogeneic hematopoietic cell transplantation. Profound T-cell …

[HTML][HTML] Improved survival after allogeneic hematopoietic stem cell transplantation in recent years. A single-center study

M Remberger, M Ackefors, S Berglund… - Biology of Blood and …, 2011 - Elsevier
We analyzed the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) over
the past 2 decades. Between 1992 and 2009, 953 patients were treated with HSCT, mainly …