Molecular drilling to combat salmonella typhi biofilm using L-Asparaginase via multiple targeting process
A Upadhyay, D Pal, A Kumar - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
ABSTRACT Objectives Salmonella Typhi biofilm condition is showing as a major public
health problem due to the development of antibiotic resistance and less available druggable …
health problem due to the development of antibiotic resistance and less available druggable …
Computational design of a multi-epitope vaccine candidate against Langya henipavirus using surface proteins
Abstract In July 2022, Langya henipavirus (LayV) was identified in febrile patients in China.
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
Advances in computational and bioinformatics tools and databases for designing and develo** a multi-epitope-based peptide vaccine
A vaccine is defined as a biologic preparation that trains the immune system, boosts
immunity, and protects against a deadly microbial infection. They have been used for …
immunity, and protects against a deadly microbial infection. They have been used for …
Enhancing explainable SARS-CoV-2 vaccine development leveraging bee colony optimised Bi-LSTM, Bi-GRU models and bioinformatic analysis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a single-stranded
RNA virus that caused the outbreak of the coronavirus disease 2019 (COVID-19). The …
RNA virus that caused the outbreak of the coronavirus disease 2019 (COVID-19). The …
Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and molecular …
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
A novel chimeric vaccine containing multiple epitopes for simulating robust immune activation against Klebsiella pneumoniae
Background Due to antibiotic resistance, the Klebsiella genus is linked to morbidity and
death, necessitating the development of a universally protective vaccine against Klebsiella …
death, necessitating the development of a universally protective vaccine against Klebsiella …
Computational design and evaluation of a polyvalent vaccine for viral nervous necrosis (VNN) in fish to combat Betanodavirus infection
Viral nervous necrosis (VNN) poses a significant threat to the aquaculture industry, causing
substantial losses and economic burdens. The disease, attributed to nervous necrosis …
substantial losses and economic burdens. The disease, attributed to nervous necrosis …
[HTML][HTML] A rational designed multi-epitope vaccine elicited robust protective efficacy against Klebsiella pneumoniae lung infection
J Liao, X Zhang, X Zeng, Z Zhao, T Sun, Z **a… - Biomedicine & …, 2024 - Elsevier
Background The emergence of drug-resistant strains of Klebsiella pneumoniae (K.
pneumoniae) has become a significant challenge in the field of infectious diseases, posing …
pneumoniae) has become a significant challenge in the field of infectious diseases, posing …
[HTML][HTML] Development of multi-epitope mRNA vaccine against Clostridioides difficile using reverse vaccinology and immunoinformatics approaches
C Tan, T Liu, S Chen, J Zhou, S Zhang, Y Hu… - Synthetic and Systems …, 2024 - Elsevier
Abstract Clostridioides difficile (C. difficile), as the major pathogen of diarrhea in healthcare
settings, has become increasingly prevalent within community populations, resulting in …
settings, has become increasingly prevalent within community populations, resulting in …
Using pectinase enzymatic peeling for obtaining high-quality Huyou (Citrus changshanensis) segments
Y Gu, J Lv, M Gouda, Y Zhu, Y He, J Chen - Journal of Food Composition …, 2024 - Elsevier
Huyou (Citrus changshanensis) is a toothsome and nutritious fruit, but its consumption is
hindered due to the nonedible segment membranes. The use of pectinase in citrus peel …
hindered due to the nonedible segment membranes. The use of pectinase in citrus peel …