Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

Increasing evidence suggests that vascular risk factors contribute to neurodegeneration,
cognitive impairment and dementia. While there is considerable overlap between features of …

CSF from the subarachnoid space moves rapidly into the brain along paravascular routes
surrounding penetrating cerebral arteries, exchanging with brain interstitial fluid (ISF) and …

Astrocytes are glial cells that are distributed throughout the central nervous system in an
arrangement optimal for chemical and physical interaction with neuronal synapses and …

Vascular dementia (VaD) is a second most common form of age-related dementia. It is
characterized by cognitive impairment associated with vascular pathology, symptoms mainly …

Abstract The World Health Organization reports that 47.5 million people are affected by
dementia worldwide. With aging populations and 7.7 million new cases each year, the …

Vascular contributions to cognitive impairment are receiving heightened attention as
potentially modifiable factors for dementias of later life. These factors have now been linked …

Vascular cognitive impairment (VCI) is the diagnostic term used to describe a
heterogeneous group of sporadic and hereditary diseases of the large and small blood …

Vascular cognitive impairment (VCI) or vascular dementia occurs as a result of brain
ischemia and represents the second most common type of dementia after Alzheimer's …

Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive
decline, attributable to cerebrovascular factors. Numerous studies have demonstrated that …