The recent impact of solid-phase synthesis on medicinally relevant benzoannelated nitrogen heterocycles
S Bräse, C Gil, K Knepper - Bioorganic & medicinal chemistry, 2002 - Elsevier
Benzoannelated heterocycles such as benzodiazepines and indoles can be prepared
efficiently through cyclization on solid supports, although no single approach is currently …
efficiently through cyclization on solid supports, although no single approach is currently …
Azo group (s) in selected macrocyclic compounds
E Wagner-Wysiecka, N Łukasik, JF Biernat… - Journal of Inclusion …, 2018 - Springer
Azobenzene derivatives due to their photo-and electroactive properties are an important
group of compounds finding applications in diverse fields. Due to the possibility of …
group of compounds finding applications in diverse fields. Due to the possibility of …
Aryl Diazonium Salt‐Triggered Cyclization and Cycloaddition Reactions: Past, Present, and Future
Aryl diazonium salts occupy a privileged role in synthetic chemistry owing to their ready
availability and versatile reactivity. While their applications in accessing diversely …
availability and versatile reactivity. While their applications in accessing diversely …
Benzodiazines: recent synthetic advances
T Mathew, AÁ Papp, F Paknia, S Fustero… - Chemical Society …, 2017 - pubs.rsc.org
Benzodiazines (diazonaphthalenes with both nitrogens in the same ring)–cinnolines (1, 2-
benzodiazine), quinazolines (1, 3-benzodiazine), phthalazines (2, 3-benzodiazine) and …
benzodiazine), quinazolines (1, 3-benzodiazine), phthalazines (2, 3-benzodiazine) and …
Catalyst-free cascade annulation of enaminones and aryl diazonium tetrafluoroboronates for cinnoline synthesis and the anti-inflammatory activity study
S Tian, Y Liu, C Wan, JP Wan… - The Journal of Organic …, 2023 - ACS Publications
A simple and concise method for the synthesis of cinnolines has been developed by the
reactions of readily available enaminones and aryl diazonium tetrafluoroboronates. The …
reactions of readily available enaminones and aryl diazonium tetrafluoroboronates. The …
Recent advances in the synthesis of biologically active cinnoline, phthalazine and quinoxaline derivatives
In the recent decades, N-heterocycles are widely used as versatile scaffolds for the
development of biologically active compounds and considered as one of the privileged …
development of biologically active compounds and considered as one of the privileged …
Acid-induced multicolor fluorescence of pyridazine derivative
M Li, Y Yuan, Y Chen - ACS applied materials & interfaces, 2018 - ACS Publications
Smart luminescent materials that are responsive to external stimuli have received
considerable attention. Here, we report a new D–A type 1, 2-pyridiazine derivative (3, 4, 5, 6 …
considerable attention. Here, we report a new D–A type 1, 2-pyridiazine derivative (3, 4, 5, 6 …
Cinnoline derivatives with biological activity
W Lewgowd, A Stanczak - Archiv der Pharmazie: An …, 2007 - Wiley Online Library
Although cinnoline belongs to a family of fairly well known heterocycles, the interest in the
study of its derivatives continues. Cinnoline compounds demonstrate interesting bioactivity …
study of its derivatives continues. Cinnoline compounds demonstrate interesting bioactivity …
Isoindolo[2,1-a]quinoxaline Derivatives, Novel Potent Antitumor Agents with Dual Inhibition of Tubulin Polymerization and Topoisomerase I
Isoindoloquinoxalines 4 and 5 were obtained by refluxing 2-(2′-aminoaryl)-1-
cyanoisoindoles 3a− e in acetic or formic acid. All derivatives were screened by the National …
cyanoisoindoles 3a− e in acetic or formic acid. All derivatives were screened by the National …
Synthesis and antimalarial evaluation of novel isocryptolepine derivatives
LR Whittell, KT Batty, RPM Wong, EM Bolitho… - Bioorganic & medicinal …, 2011 - Elsevier
A series of mono-and di-substituted analogues of isocryptolepine have been synthesized
and evaluated for in vitro antimalarial activity against chloroquine sensitive (3D7) and …
and evaluated for in vitro antimalarial activity against chloroquine sensitive (3D7) and …