Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …

To support an ever-increasing population, modern agriculture faces numerous challenges
that pose major threats to global food and energy security. Plant-associated microbes, with …

Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as
structural components of the virion. These enzymes appear as tail spike proteins (TSPs) …

In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Emergence of antibiotic resistance presents a major setback to global health, and shortage
of antibiotic pipelines has created an urgent need for development of alternative therapeutic …

Biofilms are complex microbial microcolonies consisting of planktonic and dormant bacteria
bound to a surface. The bacterial cells within the biofilm are embedded within the …

The increasing drug resistance of bacteria to commonly used antibiotics creates the need to
search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly …

In an era of proliferating multidrug resistant bacterial infections that are exhausting the
capacity of existing chemical antibiotics and in which the development of new antibiotics is …

The alarming rise in antimicrobial resistance coupled with a lack of innovation in antibiotics
has renewed interest in the development of alternative therapies to combat bacterial …