The mitochondria contain their own genome derived from an alphaproteobacterial
endosymbiont. From thousands of protein-coding genes originally encoded by their …

Abstract Background PacBio high fidelity (HiFi) sequencing reads are both long (15–20 kb)
and highly accurate (> Q20). Because of these properties, they have revolutionised genome …

Genome sequence assemblies provide the basis for our understanding of biology.
Generating error-free assemblies is therefore the ultimate, but sadly still unachieved goal of …

High-quality and complete reference genome assemblies are fundamental for the
application of genomics to biology, disease, and biodiversity conservation. However, such …

The current human reference genome, GRCh38, represents over 20 years of effort to
generate a high-quality assembly, which has benefitted society,. However, it still has many …

The chicken continues to hold its position as a leading model organism within many areas of
research, as well as being a major source of protein for human consumption. The First …

The Earth BioGenome Project aims to produce reference genomes for all~ 1.8 million known
eukaryotic species over the next decade 1–4. Achieving this goal will require the current …

Background Phylogenetic gaps of public databases of reference sequences are a major
obstacle for comparative genomics and management of marine resources, particularly in the …

Vertebrate mitochondrial genomes have been extensively studied for genetic and
evolutionary purposes, these are normally believed to be extremely conserved, however …

Sharks occupy diverse ecological niches and play critical roles in marine ecosystems, often
acting as apex predators. They are considered a slow-evolving lineage and have been …