Microbial steroid transformations: current state and prospects

MV Donova, OV Egorova - Applied microbiology and biotechnology, 2012 - Springer
Studies of steroid modifications catalyzed by microbial whole cells represent a well-
established research area in white biotechnology. Still, advances over the last decade in …

An overview on alcohol oxidases and their potential applications

P Goswami, SSR Chinnadayyala… - Applied Microbiology …, 2013 - Springer
Abstract Alcohol oxidases (Alcohol: O 2 Oxidoreductase; EC 1.1. 3. x) are flavoenzymes that
catalyze the oxidation of alcohols to the corresponding carbonyl compounds with a …

Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation

JF Aparicio, EG Barreales, TD Payero… - Applied microbiology …, 2016 - Springer
Pimaricin (natamycin) is a small polyene macrolide antibiotic used worldwide. This efficient
antimycotic and antiprotozoal agent, produced by several soil bacterial species of the genus …

Actinomycete-derived polyketides as a source of antibiotics and lead structures for the development of new antimicrobial drugs

HL Robertsen, EM Musiol-Kroll - Antibiotics, 2019 - mdpi.com
Actinomycetes are remarkable producers of compounds essential for human and veterinary
medicine as well as for agriculture. The genomes of those microorganisms possess several …

Use of elicitors to enhance or activate the antibiotic production in streptomyces

G Zong, J Fu, P Zhang, W Zhang, Y Xu… - Critical Reviews in …, 2022 - Taylor & Francis
Streptomyces is the largest and most significant genus of Actinobacteria, comprising 961
species. These Gram-positive bacteria produce many versatile and important bioactive …

Cholesterol oxidase: biotechnological applications

L Pollegioni, L Piubelli, G Molla - The FEBS journal, 2009 - Wiley Online Library
Cholesterol oxidase is a bacterial FAD‐containing flavooxidase that catalyzes the first
reaction in cholesterol catabolism. Indeed, this enzyme catalyzes two reactions: the …

PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis

N Anton, J Santos-Aberturas, MV Mendes… - …, 2007 - microbiologyresearch.org
Sequencing of the DNA region on the left fringe of the pimaricin gene cluster revealed the
presence of a 579 bp gene, pimM, whose deduced product (192 aa) was found to have …

Characteristics and biotechnological applications of microbial cholesterol oxidases

N Doukyu - Applied Microbiology and Biotechnology, 2009 - Springer
Microbial cholesterol oxidase is an enzyme of great commercial value, widely employed by
laboratories routinely devoted to the determination of cholesterol concentrations in serum …

Initial step in the catabolism of cholesterol by Mycobacterium smegmatis mc2155

I Uhía, B Galán, V Morales… - Environmental …, 2011 - Wiley Online Library
The first step in the catabolism of cholesterol, ie the transformation of cholesterol into
cholestenone, has been investigated in Mycobacterium smegmatis. In silico analysis …

Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA

O Yushchuk, I Ostash, E Mösker, I Vlasiuk, M Deneka… - Scientific reports, 2021 - nature.com
Actinobacteria are among the most prolific sources of medically and agriculturally important
compounds, derived from their biosynthetic gene clusters (BGCs) for specialized …