Myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently
identified autoimmune disorder that presents in both adults and children as CNS …

Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …

Abstract CD4+ T helper (Th) cells are critical for proper immune cell homeostasis and host
defense, but are also major contributors to pathology of autoimmune and inflammatory …

Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
(CNS) leading to the progressive destruction of the myelin sheath surrounding axons. It can …

▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …

To assess the importance of B cell control of T cell differentiation, we analyzed the course of
the T helper type 1 (TH1)-driven disease experimental autoimmune encephalomyelitis in …

Autoreactive T cell responses have a crucial role in central nervous system (CNS) diseases
such as multiple sclerosis. Recent data indicate that CNS autoimmunity can be mediated by …

Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been found in
some cases diagnosed as seronegative neuromyelitis optica spectrum disorder (NMOSD) …

Cannabinoids are a group of compounds that mediate their effects through cannabinoid
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …

Background Serum autoantibodies against the water channel aquaporin-4 (AQP4) are
important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO) …