Recent innovations in bacterial infection detection and treatment
C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …
Exploring pathological link between antimicrobial and amyloid peptides
Amyloid peptides (AMYs) and antimicrobial peptides (AMPs) are considered as the two
distinct families of peptides, characterized by their unique sequences, structures, biological …
distinct families of peptides, characterized by their unique sequences, structures, biological …
Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
It is unclear how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
leads to the strong but ineffective inflammatory response that characterizes severe …
leads to the strong but ineffective inflammatory response that characterizes severe …
Addressing MRSA infection and antibacterial resistance with peptoid polymers
Abstract Methicillin-Resistant Staphylococcus aureus (MRSA) induced infection calls for
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …
Stable peptide-assembled nanozyme mimicking dual antifungal actions
Y Yuan, L Chen, K Song, M Cheng, L Fang… - Nature …, 2024 - nature.com
Natural antimicrobial peptides (AMPs) and enzymes (AMEs) are promising non-antibiotic
candidates against antimicrobial resistance but suffer from low efficiency and poor stability …
candidates against antimicrobial resistance but suffer from low efficiency and poor stability …
SARS-CoV-2 spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity
There is a link between high lipopolysaccharide (LPS) levels in the blood and the metabolic
syndrome, and metabolic syndrome predisposes patients to severe COVID-19. Here, we …
syndrome, and metabolic syndrome predisposes patients to severe COVID-19. Here, we …
The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
J Di Domizio, C Belkhodja, P Chenuet, A Fries… - Nature …, 2020 - nature.com
Skin wounds heal by coordinated induction of inflammation and tissue repair, but the
initiating events are poorly defined. Here we uncover a fundamental role of commensal skin …
initiating events are poorly defined. Here we uncover a fundamental role of commensal skin …
Cathelicidins modulate TLR-activation and inflammation
MR Scheenstra, RM Van Harten… - Frontiers in …, 2020 - frontiersin.org
Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …
highly engage into research on alternative strategies to the traditional small molecule …
Antimicrobial peptides: An overview of their structure, function and mechanism of action
R Zhang, L Xu, C Dong - Protein and Peptide Letters, 2022 - ingentaconnect.com
In recent years, the antibiotic resistance of pathogenic bacteria has become an increasing
public health threat. Finding alternatives to antibiotics may be an effective solution to the …
public health threat. Finding alternatives to antibiotics may be an effective solution to the …