Cancer biomarker detection: recent achievements and challenges
L Wu, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
The early detection of cancer can significantly reduce cancer mortality and saves lives. Thus,
a great deal of effort has been devoted to the exploration of new technologies to detect early …
a great deal of effort has been devoted to the exploration of new technologies to detect early …
Nanopore technology and its applications in gene sequencing
B Lin, J Hui, H Mao - Biosensors, 2021 - mdpi.com
In recent years, nanopore technology has become increasingly important in the field of life
science and biomedical research. By embedding a nano-scale hole in a thin membrane and …
science and biomedical research. By embedding a nano-scale hole in a thin membrane and …
Recent progress in solid‐state nanopores
K Lee, KB Park, HJ Kim, JS Yu, H Chae… - Advanced …, 2018 - Wiley Online Library
The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …
Detection and map** of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA
Precise and efficient map** of epigenetic markers on DNA may become an important
clinical tool for prediction and identification of ailments. Methylated CpG sites are involved in …
clinical tool for prediction and identification of ailments. Methylated CpG sites are involved in …
Slow DNA transport through nanopores in hafnium oxide membranes
We present a study of double-and single-stranded DNA transport through nanopores
fabricated in ultrathin (2–7 nm thick) freestanding hafnium oxide (HfO2) membranes. The …
fabricated in ultrathin (2–7 nm thick) freestanding hafnium oxide (HfO2) membranes. The …
Oxford Nanopore sequencing: new opportunities for plant genomics?
DNA sequencing was dominated by Sanger's chain termination method until the mid-2000s,
when it was progressively supplanted by new sequencing technologies that can generate …
when it was progressively supplanted by new sequencing technologies that can generate …
Optoelectronic control of surface charge and translocation dynamics in solid-state nanopores
Nanopores can be used to detect and analyse biomolecules. However, controlling the
translocation speed of molecules through a pore is difficult, which limits the wider application …
translocation speed of molecules through a pore is difficult, which limits the wider application …
Electroosmotic trap against the electrophoretic force near a protein nanopore reveals peptide dynamics during capture and translocation
We report on the ability to control the dynamics of a single peptide capture and passage
across a voltage-biased, α-hemolysin nanopore (α-HL), under conditions that the …
across a voltage-biased, α-hemolysin nanopore (α-HL), under conditions that the …
Challenges in DNA motion control and sequence readout using nanopore devices
Nanopores are being hailed as a potential next-generation DNA sequencer that could
provide cheap, high-throughput DNA analysis. In this review we present a detailed summary …
provide cheap, high-throughput DNA analysis. In this review we present a detailed summary …
The design and characterization of multifunctional aptamer nanopore sensors
Aptamer-modified nanomaterials provide a simple, yet powerful sensing platform when
combined with resistive pulse sensing technologies. Aptamers adopt a more stable tertiary …
combined with resistive pulse sensing technologies. Aptamers adopt a more stable tertiary …