Bioactive lipids, inflammation and chronic diseases

A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

Aberrations in peripheral inflammatory cytokine levels in Parkinson disease: a systematic review and meta-analysis

XY Qin, SP Zhang, C Cao, YP Loh, Y Cheng - JAMA neurology, 2016 - jamanetwork.com
Importance The association of nonmotor features and Parkinson disease (PD) is
increasingly recognized. Evidence suggests that inflammation may play a role in PD …

[HTML][HTML] Parkinson's disease and its management: part 1: disease entity, risk factors, pathophysiology, clinical presentation, and diagnosis

G DeMaagd, A Philip - Pharmacy and therapeutics, 2015 - ncbi.nlm.nih.gov
Parkinson’s Disease and Its Management - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …

Emerging therapies in Parkinson disease—repurposed drugs and new approaches

A Elkouzi, V Vedam-Mai, RS Eisinger… - Nature Reviews …, 2019 - nature.com
Parkinson disease (PD) treatment options have conventionally focused on dopamine
replacement and provision of symptomatic relief. Current treatments cause undesirable …

[HTML][HTML] Autophagy and apoptosis dysfunction in neurodegenerative disorders

S Ghavami, S Shojaei, B Yeganeh, SR Ande… - Progress in …, 2014 - Elsevier
Autophagy and apoptosis are basic physiologic processes contributing to the maintenance
of cellular homeostasis. Autophagy encompasses pathways that target long-lived cytosolic …

Targeting microglial activation states as a therapeutic avenue in Parkinson's disease

SR Subramaniam, HJ Federoff - Frontiers in aging neuroscience, 2017 - frontiersin.org
Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …

Implications of glial nitric oxide in neurodegenerative diseases

JE Yuste, E Tarragon, CM Campuzano… - Frontiers in cellular …, 2015 - frontiersin.org
Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease

V Brochard, B Combadière, A Prigent… - The Journal of …, 2008 - Am Soc Clin Investig
Parkinson disease (PD) is a neurodegenerative disorder characterized by a loss of
dopamine-containing neurons. Mounting evidence suggests that dopaminergic cell death is …

The scientific and clinical basis for the treatment of Parkinson disease (2009)

CW Olanow, MB Stern, K Sethi - Neurology, 2009 - AAN Enterprises
Parkinson disease (PD) is an age-related neurodegenerative disorder that affects as many
as 1–2% of persons aged 60 years and older. With the aging of the population, the …

Acute migraine medications and evolution from episodic to chronic migraine: A longitudinal population‐based study

ME Bigal, D Serrano, D Buse, A Scher… - … : The Journal of …, 2008 - Wiley Online Library
Background.—Though symptomatic medication overuse is believed to play a major role in
progression from episodic to chronic or transformed migraine (TM), population‐based …