Acute pancreatitis is a common indication for hospital admission, increasing in incidence,
including in children, pregnancy and the elderly. Moderately severe acute pancreatitis with …

Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …

The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …

Chronic arsenic exposure is a significantly risk factor for pancreatic dysfunction and type 2
diabetes (T2D). Ferroptosis is a newly identified iron-dependent form of oxidative cell death …

Severe acute pancreatitis (SAP), a serious inflammatory disease of the pancreas, can easily
lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction …

Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma
triglyceride concentration (seTG) is> 1.7 mM. HTG can be categorized as mild to very severe …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease that
affects approximately one-quarter of the global adult population, posing a significant threat …

Premature activation of digestive enzymes in the pancreas has been linked to development
of pancreatitis for more than a century. Recent development of novel models to study the …

Aging is associated with cell senescence and is the major risk factor for AD. We
characterized premature cell senescence in postmortem brains from non-diseased controls …

Endoplasmic reticulum (ER) stress and mitochondrial dysfunction play a pivotal role in the
pathological process of sepsis-induced acute lung injury (ALI). Quercetin has been proved …