The reprimo gene family: a novel gene lineage in gastric cancer with tumor suppressive properties
The reprimo (RPRM) gene family is a group of single exon genes present exclusively within
the vertebrate lineage. Two out of three members of this family are present in humans …
the vertebrate lineage. Two out of three members of this family are present in humans …
The inflamm-aging model identifies key risk factors in atherosclerosis
Y He, Y Chen, L Yao, J Wang, X Sha, Y Wang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Atherosclerosis, one of the main threats to human life and health, is driven by
abnormal inflammation (ie, chronic inflammation or oxidative stress) during accelerated …
abnormal inflammation (ie, chronic inflammation or oxidative stress) during accelerated …
RPRM deletion preserves hematopoietic regeneration by promoting EGFR‐dependent DNA repair and hematopoietic stem cell proliferation post ionizing radiation
Z Li, Z Zhou, S Tian, K Zhang, G An… - Cell Biology …, 2022 - Wiley Online Library
Reprimo (RPRM), a target gene of p53, is a known tumor suppressor. DNA damage induces
RPRM, which triggers p53‐dependent G2 arrest by inhibiting cyclin B1/Cdc2 complex …
RPRM, which triggers p53‐dependent G2 arrest by inhibiting cyclin B1/Cdc2 complex …
Reprimo (RPRM) as a Potential Preventive and Therapeutic Target for Radiation-Induced Brain Injury via Multiple Mechanisms
Z Ye, J Wang, W Shi, Z Zhou, Y Zhang, J Wang… - International Journal of …, 2023 - mdpi.com
Patients receiving cranial radiotherapy for primary and metastatic brain tumors may
experience radiation-induced brain injury (RIBI). Thus far, there has been a lack of effective …
experience radiation-induced brain injury (RIBI). Thus far, there has been a lack of effective …
The reprimo-like gene is an epigenetic-mediated tumor suppressor and a candidate biomarker for the non-invasive detection of gastric cancer
MA Alarcón, W Olivares, M Córdova-Delgado… - International Journal of …, 2020 - mdpi.com
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Here, we
evaluated the role of RPRML and whether its regulation by DNA methylation is a potential …
evaluated the role of RPRML and whether its regulation by DNA methylation is a potential …
Zebrafish as a model for investigating antiviral innate immunity
XM Wu, SY Zheng, MX Chang - Antiviral Innate Immunity, 2024 - Springer
Zebrafish is a widely used model organism in genetics, developmental biology, pathology,
and immunology research. Due to their fast reproduction, large numbers, transparent early …
and immunology research. Due to their fast reproduction, large numbers, transparent early …
Expression of RPRM/rprm in the Olfactory System of Embryonic Zebrafish (Danio rerio)
The Reprimo (RPRM) family is composed of highly conserved single-exon genes. The
expression pattern of this gene family has been recently described during zebrafish (Danio …
expression pattern of this gene family has been recently described during zebrafish (Danio …
COVID-19 and alcohol use disorder: Putative differential gene expression patterns that might be associated with neurological complications
Background Several lines of evidence suggest that SARS-CoV-2 invasion of the central
nervous system leads to meningitis and encephalopathy syndromes. Additionally, chronic …
nervous system leads to meningitis and encephalopathy syndromes. Additionally, chronic …
The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish
K Stanic, G Reig, RJ Figueroa, PA Retamal… - Scientific Reports, 2019 - nature.com
The Reprimo gene family comprises a group of single-exon genes for which their
physiological function remains poorly understood. Heretofore, mammalian Reprimo (RPRM) …
physiological function remains poorly understood. Heretofore, mammalian Reprimo (RPRM) …
Sex-specific thermoregulatory effects of estrogen signaling in Reprimo lineage cells
Menopause affects over a million individuals annually and is characterized by variable and
declining ovarian hormones. Decreasing estrogen levels impact energy homeostasis and …
declining ovarian hormones. Decreasing estrogen levels impact energy homeostasis and …