The microbiome in inflammatory bowel disease: current status and the future ahead
Studies of the roles of microbial communities in the development of inflammatory bowel
disease (IBD) have reached an important milestone. A decade of genome-wide association …
disease (IBD) have reached an important milestone. A decade of genome-wide association …
[HTML][HTML] Inflammatory bowel disease: pathogenesis
YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …
Microbial influences in inflammatory bowel diseases
RB Sartor - Gastroenterology, 2008 - Elsevier
The predominantly anaerobic microbiota of the distal ileum and colon contain an
extraordinarily complex variety of metabolically active bacteria and fungi that intimately …
extraordinarily complex variety of metabolically active bacteria and fungi that intimately …
[HTML][HTML] The role of neutrophils during intestinal inflammation
BM Fournier, CA Parkos - Mucosal immunology, 2012 - Elsevier
Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …
Intestinal barrier dysfunction in inflammatory bowel diseases
The etiology of human inflammatory bowel diseases (IBDs) is believed to involve
inappropriate host responses to the complex commensal microbial flora in the gut, although …
inappropriate host responses to the complex commensal microbial flora in the gut, although …
[HTML][HTML] Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?
GL Hold, M Smith, C Grange, ER Watt… - World journal of …, 2014 - ncbi.nlm.nih.gov
Our understanding of the microbial involvement in inflammatory bowel disease (IBD)
pathogenesis has increased exponentially over the past decade. The development of newer …
pathogenesis has increased exponentially over the past decade. The development of newer …
Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in …
Intestinal bacteria are implicated increasingly as a pivotal factor in the development of
Crohn's disease, but the specific components of the complex polymicrobial enteric …
Crohn's disease, but the specific components of the complex polymicrobial enteric …
Partial enteral nutrition with a Crohn's disease exclusion diet is effective for induction of remission in children and young adults with Crohn's disease
R Sigall-Boneh, T Pfeffer-Gik, I Segal… - Inflammatory bowel …, 2014 - academic.oup.com
Background Exclusive enteral nutrition is effective for inducing remission in active pediatric
Crohn's disease. Partial enteral nutrition (PEN) with free diet is ineffective for inducing …
Crohn's disease. Partial enteral nutrition (PEN) with free diet is ineffective for inducing …
Dysbiotic events in gut microbiota: impact on human health
S Schippa, MP Conte - Nutrients, 2014 - mdpi.com
The human body is colonized by a large number of microbes coexisting peacefully with their
host. The most colonized site is the gastrointestinal tract (GIT). More than 70% of all the …
host. The most colonized site is the gastrointestinal tract (GIT). More than 70% of all the …
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
AM Smith, FZ Rahman, BH Hayee, SJ Graham… - Journal of Experimental …, 2009 - rupress.org
The cause of Crohn's disease (CD) remains poorly understood. Counterintuitively, these
patients possess an impaired acute inflammatory response, which could result in delayed …
patients possess an impaired acute inflammatory response, which could result in delayed …