An increasing number of epilepsies are being attributed to variants in genes with epigenetic
functions. The products of these genes include factors that regulate the structure and …

Neuroinflammation is a cause of neurodevelopmental disorders such as autism spectrum
disorders, fetal alcohol syndrome, and cerebral palsy. Converging lines of evidence from …

Rett syndrome (RTT) is defined as a rare disease caused by mutations of the methyl-CpG
binding protein 2 (MECP2). It is one of the most common causes of genetic mental …

Autism spectrum disorder (ASD) has become a common neurodevelopmental disorder. The
heterogeneity of ASD poses great challenges for its research and clinical translation. On the …

Maternal diabetes has been associated with a greater risk of neurodevelopmental disorders
in offspring. It has been established that hyperglycemia alters the expression of genes and …

Mutations occurring in the MeCp2, CDKL5 and BDNF genes have been linked to
epileptogenesis in various epilepsy syndromes. This study employed bioinformatics analysis …

Aim This study aims to address the key question of the causal relationship between serum
levels of 25-hydroxyvitamin D (vitamin D) and autism spectrum disorders (ASD). Methods …

Rett syndrome (RTT) is an X-linked neurological disorder caused by mutations in the
transcriptional regulator MECP2. Mecp2 loss-of-function leads to the disruption of many …

Rett syndrome (RTT) is a devastating neurodevelopmental disorder caused by mutations in
the X-linked MECP2 gene, primarily acting as transcriptional repressor. Although RTT …