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Applications of synthetic biology in medical and pharmaceutical fields
X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …
bioproperties. During the past decades, progresses have been made to build delicate …
Transcription-factor-based biosensor engineering for applications in synthetic biology
Transcription-factor-based biosensors (TFBs) are often used for metabolite detection,
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …
The all-E. coliTXTL toolbox 3.0: new capabilities of a cell-free synthetic biology platform
D Garenne, S Thompson, A Brisson… - Synthetic …, 2021 - academic.oup.com
The new generation of cell-free gene expression systems enables the prototy** and
engineering of biological systems in vitro over a remarkable scope of applications and …
engineering of biological systems in vitro over a remarkable scope of applications and …
A comprehensive review on the applications of nano-biosensor-based approaches for non-communicable and communicable disease detection
The outstretched applications of biosensors in diverse domains has become the reason for
their attraction for scientific communities. Because they are analytical devices, they can …
their attraction for scientific communities. Because they are analytical devices, they can …
Recent trends in chemical sensors for detecting toxic materials
Industrial development has led to the widespread production of toxic materials, including
carcinogenic, mutagenic, and toxic chemicals. Even with strict management and control …
carcinogenic, mutagenic, and toxic chemicals. Even with strict management and control …
Development of Cas12a-based cell-free small-molecule biosensors via allosteric regulation of CRISPR array expression
Cell-free biosensors can detect various molecules, thus promising to transform the
landscape of diagnostics. Here, we developed a simple, rapid, sensitive, and field …
landscape of diagnostics. Here, we developed a simple, rapid, sensitive, and field …
[HTML][HTML] Biotechnology applications of cell-free expression systems
Cell-free systems are a rapidly expanding platform technology with an important role in the
engineering of biological systems. The key advantages that drive their broad adoption are …
engineering of biological systems. The key advantages that drive their broad adoption are …
Synthetic cells in biomedical applications
Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …
These features include directed localization, sense‐and‐respond behavior, gene …
Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes
EA Phillips, AD Silverman, A Joneja, M Liu… - Nature Biomedical …, 2023 - nature.com
Nucleic acid assays are not typically deployable in point-of-care settings because they
require costly and sophisticated equipment for the control of the reaction temperature and for …
require costly and sophisticated equipment for the control of the reaction temperature and for …
[HTML][HTML] Towards detection of SARS-CoV-2 RNA in human saliva: A paper-based cell-free toehold switch biosensor with a visual bioluminescent output
The COVID-19 pandemic has illustrated the global demand for rapid, low-cost, widely
distributable and point-of-care nucleic acid diagnostic technologies. Such technologies …
distributable and point-of-care nucleic acid diagnostic technologies. Such technologies …